伊立替康治疗儿童复发肝母细胞瘤的探索研究

常健,张语桐,钟晓丹,王立哲

中国当代儿科杂志 ›› 2013, Vol. 15 ›› Issue (7) : 588-590.

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中国当代儿科杂志 ›› 2013, Vol. 15 ›› Issue (7) : 588-590. DOI: 10.7499/j.issn.1008-8830.2013.07.019
临床经验

伊立替康治疗儿童复发肝母细胞瘤的探索研究

  • 常健,张语桐,钟晓丹,王立哲
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Preliminary study on the efficacy of irinotecan in the treat,emt of childhood relapsed hepatoblastoma

  • CHANG Jian, ZHANG Yu-Tong, ZHONG Xiao-Dan, WANG Li-Zhe
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常健,张语桐,钟晓丹,王立哲. 伊立替康治疗儿童复发肝母细胞瘤的探索研究[J]. 中国当代儿科杂志. 2013, 15(7): 588-590 https://doi.org/10.7499/j.issn.1008-8830.2013.07.019
CHANG Jian, ZHANG Yu-Tong, ZHONG Xiao-Dan, WANG Li-Zhe. Preliminary study on the efficacy of irinotecan in the treat,emt of childhood relapsed hepatoblastoma[J]. Chinese Journal of Contemporary Pediatrics. 2013, 15(7): 588-590 https://doi.org/10.7499/j.issn.1008-8830.2013.07.019

参考文献

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[2]Vassal G, Doz F, Frappaz D,Imadalou K, Sicard E, Santos A, et al. A phase I study of irinotecan as a 3-week schedule in children with refractory or recurrent solid tumors[J]. J Clin Oncol, 2003, 21(20): 3844-3852.

[3]Bomgaars LR, Kerr J, Berg S, Kuttesch J, Klenke R, Blaney SM. A phase I study of irinotecan administered on a weekly schedule in pediatric patients[J]. Pediatr Blood Cancer, 2006, 46(1): 50-55.

[4]Palmer RD, Williams DM. Dramatic response of multiply relapsed hepatoblastoma to irinotecan (CPT-11) [J]. Med Pediatr Oncol, 2003,41(1):78-80.

[5]Roebuck DJ, Aronson D, Clapuyt P, Czauderna P, de Ville de Goyet J, Gauthier F, et al. 2005 PRETEXT: a revised staging system for primary malignant liver tumors of childhood developed by the SIOPEL group[J]. Pediar Radiol, 2007, 37(2): 123-132. 

[6]Bomgaars LR, Bernstein M, Krailo M, Kadota R, Das S, Chen Z, et al. Phase II trial of irinotecan in children with refractory solid tumors: a Children′s Oncology Group Study[J]. J Clin Oncol, 2007, 25( 29): 4622-4627.

[7]Qayed M, Powell C, Moran ER, Haugen M, Katzenstein HM. Iriontecan as maintenance therapy in high-risk hepatoblastoma[J]. Pediatr Blood Cancer, 2010, 54(5):761-763.

[8]Stringer AM, Gibson RJ, Bowen JM, Logan RM, Ashton K, Yeoh AS, et al. Irinotecan-induced mucositis manifesting as diarrheea corresponds with an amended intestinal flora and mucin profile[J]. Int J Exp Pathol, 2009, 90(5): 489-499.

[9]Park JO, Lee SI, Song SY, Kim K, Kim WS, Jung CW, et al. Measuring response in solid tumors: comparison of RECIST and WHO response criteria[J]. Jpn J Clin Oncol, 2003, 33(10): 533-537.

[10]NCI. Common Terminology Criteria for Adverse Events (CTCAE)[EB/OL]. Available at: http://evs.nci.nih.gov/ftp1/CTCAE/About. html. Accessed May, 17, 2010.

[11]Perilongo G, Shafford E, Maibach R, Aronson D, Brugières L, Brock P, et al. Risk-adapted treatment for childhood hepatoblastoma.final report of the second study of the International Society of Pacdiatric Oncologu-SIOPEL2[J]. Eur J Cancer, 2004, 40(3): 411-421.

[12]潘慈,汤静燕,陈静,薛惠良,董璐,周敏,等. 14例肝母细胞瘤患儿的临床疗效观察[J].中国当代儿科杂志,2009,11(8):659-662.

[13]魏艇,扬体泉,罗意革,董淳强. 14例儿童肝母细胞瘤综合治疗的疗效观察[J].中国当代儿科杂志,2009,11(6):456-459.

[14]Haeberle B, Schweinitz DV. Treatment of hepatoblastoma in the German cooperative pediatric liver tumor studies[J]. Front Bissci(Elite Ed), 2012, 4: 493-498.

[15]Wagner LM, Perentesis JP, Reid JM, Ames MM, Safgren SL, Nelson MD Jr,et al. Phase Ⅰtrial of two schedules of vincristine, oral irinotecan, and temozolomide (VOIT) for children with relapsed or refractory solid tumors: a Children′s Oncology Group phase Ⅰconsortium study[J]. Pediatr Blood Cancer, 2010, 54(4): 534-545.

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