高剂量拓扑替康联合环磷酰胺和长春新碱治疗儿童难治性神经母细胞瘤

常健; 张语桐; 王立哲; 钟晓丹

doi:10.7499/j.issn.1008-8830.2014.02.005

PDF(1158 KB)

HTML

中国当代儿科杂志 ›› 2014, Vol. 16 ›› Issue (2) : 120-123. DOI: 10.7499/j.issn.1008-8830.2014.02.005

血液肿瘤专题

高剂量拓扑替康联合环磷酰胺和长春新碱治疗儿童难治性神经母细胞瘤

常健, 张语桐, 王立哲, 钟晓丹

作者信息 +

Management of refractory neuroblastoma with high-dose topotecan plus cyclophosphamide and vincristine

CHANG Jian, ZHANG Yu-Tong, WANG Li-Zhe, et al.

Author information +

文章历史 +

摘要

无

Abstract

No abstract available

引用本文

EndNote

Ris (Procite)

Bibtex

导出引用

常健, 张语桐, 王立哲, 钟晓丹. 高剂量拓扑替康联合环磷酰胺和长春新碱治疗儿童难治性神经母细胞瘤[J]. 中国当代儿科杂志. 2014, 16(2): 120-123 https://doi.org/10.7499/j.issn.1008-8830.2014.02.005

CHANG Jian, ZHANG Yu-Tong, WANG Li-Zhe, et al.. Management of refractory neuroblastoma with high-dose topotecan plus cyclophosphamide and vincristine[J]. Chinese Journal of Contemporary Pediatrics. 2014, 16(2): 120-123 https://doi.org/10.7499/j.issn.1008-8830.2014.02.005

参考文献

[1] Simon T, Langle A, Harnischmacher U, et al. Topotecan, cyclophosphamide, and etoposide (TCE) in the treatment of highrisk neuroblastoma. Results of a phase-Ⅱ trial[J]. J Cancer Res Clin Oncol, 2007, 133(9): 653-661.
[2] Santana VM, Furman WL, Billups CA, et al. Improved response in high-risk neuroblastoma with protracted topotecan administration using apharmacokinetically guided dosing approach[J]. J Clin Oncol, 2005, 23(18): 4039-4047.
[3] Brisse HJ, McCarvile MB, Granata C, et al. Guidelines for imaging and staging of neuroblastic tumors: consensus report from the International Neuroblastoma Risk Group Project[J]. Radiology, 2011, 261(1): 243-257.
[4] Mueller S, Matthay KK. Neuroblastoma: biology and staging[J]. Curr Oncol Rep, 2009, 11(6): 431-438.
[5] Berthold F, Hero B, Kremens B, et al. Long-term results and risk profiles of patients in five consecutive trials(1979-1997) with stage 4 neuroblastoma over 1 year of age[J]. Cancer Lett, 2003, 197(1-2): 11-17.
[6] Broeur GM, Pritchard J, Berthold F, et al. Revisions of the international criteria for neuroblastoma diagnosis, staging, and response to treatment[J]. J Clin Oncol, 1993, 11(8): 1466-1477.
[7] Kushner BH, Kramer K, Modak S, et al. Differential impact of high-dose cyclophosphamide, topotecan, and vincristine in clinical subsets of patients with chemoresistant neuroblastoma[J]. Cancer, 2010, 116(12): 3054-3060.
[8] NCI. CTCAE[EB/OL].[May 17, 2010]. http://evs.nci.nih.gov/ftp1/ CTCAE/About. Html.
[9] 雷琦, 唐锁勤, 王天有. 拓扑替康对HPB-AM 细胞MAGE 基因表达的影响[J]. 中国当代儿科杂志, 2009, 11(8): 679-682.
[10] Kaufmann SH, Peereboom D, Buckwalter CA, et al. Cytotoxic effects of topotecan combined with various anticancer agents in human cancer cell lines[J]. J Natl Cancer Inst, 1996, 88(11): 734-741.
[11] Carol H, Houghton PJ, Morton CL, et al. Initial testing of topotecan by the pediatric preclinical testing program[J]. Pediatr Blood Cancer, 2010, 54(5): 707-715.
[12] Kretschmar CS, Kletzel M, Murray K, et al. Response to paclitaxel, topotecan, and topotecan-cyclophosphamide in children with untreated disseminated neuroblastoma treated in an upfront phase Ⅱ investigational window: a pediatric oncology group study[J]. J Clin Oncol, 2004, 22(20): 4119-4126.
[13] Simon T, Langler A, Berthold F, et al. Topotecan and etoposide in the treatment of relapsed high-risk neuroblastoma: results of a phase 2 trial[J]. J Pediatr Hematol Oncol, 2007, 29(2): 101-106.
[14] London WB, Frantz CN, Campbell LA, et al. Phase Ⅱ randomized comparison of topotecan plus cyclophosphamide versus topotecan alone in children with recurrent or refractory neuroblastoma: a Children's Oncology Group study[J]. J Clin Oncol, 2010, 28(24): 3808-3815.
[15] De Ioris MA, Castellano A, Ⅱari I, et al. Short topotecan-based induction regimen in newly diagnosed high-risk neuroblastoma[J]. Eur J Cancer, 2011, 47(4): 572-578.
[16] Thompsn J, George EO, Poquette CA, et al. Synergy of topotecan in combination with vincristine for treatment of pediatric solid tumor xenografts[J]. Clin Cancer Res, 1999, 5(11): 3617-3631.
[17] 朱琪琦, 刘英, 冯晨, 等. 神经母细胞瘤远期复发临床研究[J]. 中国当代儿科杂志, 2010, 12(12): 995-997.
[18] Maris JM. Recent advances in neuroblastoma[J]. N Engl J Med, 2010, 363(23): 2202-2211.