目的 婴儿全身运动（GMs）质量评估技术是预测婴儿脑功能异常的有价值的工具，该研究旨在探讨影响婴儿 GMs 质量的高危因素。方法 分别选取 618 例扭动运动阶段和 539 例不安运动阶段婴儿进行 GMs 评估。 采用单因素方差分析、卡方检验及多因素 logistic 回归分析调查影响婴儿 GMs 质量的高危因素。结果 扭动运动阶段，多因素 logistic 回归分析显示有统计学意义的影响因素为出生胎龄（OR=0.762，P<0.001）、出生体重（OR=0.264，P<0.001）、重度窒息（OR=2.445，P=0.012）、宫内窘迫（OR=4.865，P<0.001）。不安运动阶段，多因素 logistic 回归分析显示有统计学意义的影响因素为出生胎龄（OR=0.786，P=0.003）、出生体重（OR=0.217，P<0.001）、重度窒息（OR=3.765，P=0.001）、高胆红素血症（OR=2.640，P=0.028）。结论 出生胎龄、出生体重、重度窒息、宫内窘迫、高胆红素血症是异常 GMs 的高危因素，应早期筛查、干预。
Abstract
Objective To investigate the high-risk factors for the quality of general movements（GMs), which has a predictive value for brain dysfunction in infants.Methods A total of 618 infants in the stage of writhing movements and 539 infants in the stage of fidgety movements were selected separately for the evaluation of GMs. The high-risk factors for the quality of GMs in infants were analyzed by ANOVA, chi-square test, and multivariate logistic regression. Results Multivariate logistic regression analysis showed that the factors significantly associated with the quality of GMs in the stage of writhing movements were gestational age（OR=0.762, P<0.001), birth weight（OR=0.264,P<0.001), severe asphyxia（OR=2.445, P=0.012), and intrauterine distress（OR=4.865, P<0.001); the factors significantly associated with the quality of GMs in the stage of fidget movements were gestational age（OR=0.786, P=0.003), birth weight（OR=0.217, P<0.001), severe asphyxia（OR=3.765, P=0.001), and hyperbilirubinemia（OR=2.640, P=0.028).Conclusion Low gestational age, low birth weight, severe asphyxia, hyperbilirubinemia and intrauterine distress are high-risk factors for abnormal GMs in infants, and early screening and intervention should be performed to reduce the incidence of abnormal nervous system sequelae.
关键词
全身运动质量 /
高危因素 /
婴儿
Key words
Quality of general movements /
High-risk factor /
Infant
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基金
滨州医学院科技发展计划资助（BY2013KJ31）；济南市科技明星计划（20120140）；山东省优秀中青年科学家科研奖励基金计划（BS2013YY011）。
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