Adverse effects of oxcarbazepine

FANG Shu; GONG Zhi-Cheng

doi:10.7499/j.issn.1008-8830.2015.04.025

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Chinese Journal of Contemporary Pediatrics ›› 2015, Vol. 17 ›› Issue (4) : 414-419. DOI: 10.7499/j.issn.1008-8830.2015.04.025

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Adverse effects of oxcarbazepine

FANG Shu¹, GONG Zhi-Cheng²

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Abstract

Oxcarbazepine is a new antiepileptic drug. The results of clinical trials suggest that oxcarbazepine is well tolerated and has less drug interactions. It is being used more and more widely in clinical practice, but its adverse effects should not be ignored. The most common adverse effects of oxcarbazepine are usually related to the central nervous system and digestive system, including fatigue, drowsiness, diplopia, dizziness, nausea and vomit. The common skin adverse reaction is rash. Long-term use of oxcarbazepine may also cause hyponatremia. This article reviews the literature from China and overseas about the adverse effets of oxcarbazepine over the last 10 years in order to find information about rational clinical use of oxcarbazepine.

Key words

Oxcarbazepine / Epilepsy / Adverse effect

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FANG Shu, GONG Zhi-Cheng. Adverse effects of oxcarbazepine[J]. Chinese Journal of Contemporary Pediatrics. 2015, 17(4): 414-419 https://doi.org/10.7499/j.issn.1008-8830.2015.04.025

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