Abstract：The three-day-old female infant was admitted to the hospital due to respiratory distress after birth. She was born premature at 36+2 weeks gestational age. Prenatal ultrasound suggested abnormal development of the fetal liver vessels, and she had dyspnea that required respiratory support after birth. Chest X-ray indicated an enlarged cardiac silhouette, and cardiac ultrasound revealed enlargement of the right atrium and right ventricle. Diagnosis of hepatic hemangioma with arteriovenous fistula was confirmed through liver ultrasound and abdominal enhanced CT. At 19 days old, she underwent ligation of the hepatic artery under general anesthesia, which led to an improvement in cardiac function and she was subsequently discharged. Genetic testing revealed a mutation in the ACVRL1 gene, which was inherited from the mother. The article primarily introduces a case of neonatal heart failure caused by hepatic hemangioma with arteriovenous fistula, and multi-disciplinary diagnosis and treatment of this disease.
HE Yue,SUN Song,YANG Lin et al. Heart failure caused by congenital hepatic hemangioma complicated with arteriovenous fistula in a neonate[J]. CJCP, 2023, 25(8): 884-888.
Sakamoto S, Kasahara M, Shigeta T, et al. Living donor liver transplantation for multiple intrahepatic portosystemic shunts after involution of infantile hepatic hemangiomas[J]. J Pediatr Surg, 2011, 46(6): 1288-1291. PMID: 21683241. DOI: 10.1016/j.jpedsurg.2011.02.061.
Wu L, Zhao L, Lu Y, et al. Interventional embolization of congenital intrahepatic shunts in children[J]. Pediatr Radiol, 2016, 46(4): 541-547. PMID: 26637318. DOI: 10.1007/s00247-015-3497-3.
Sutcliffe R, Mieli-Vergani G, Dhawan A, et al. A novel treatment of congenital hepatoportal arteriovenous fistula[J]. J Pediatr Surg, 2008, 43(3): 571-573. PMID: 18358306. DOI: 10.1016/j.jpedsurg.2005.07.005.
Alonso-Gamarra E, Parrón M, Pérez A, et al. Clinical and radiologic manifestations of congenital extrahepatic portosystemic shunts: a comprehensive review[J]. Radiographics, 2011, 31(3): 707-722. PMID: 21571652. DOI: 10.1148/rg.313105070.
Masarone D, Valente F, Rubino M, et al. Pediatric heart failure: a practical guide to diagnosis and management[J]. Pediatr Neonatol, 2017, 58(4): 303-312. PMID: 28279666. DOI: 10.1016/j.pedneo.2017.01.001.
Marra P, Dulcetta L, Carbone FS, et al. Arterioportal fistulas (APFs) in pediatric patients: single center experience with interventional radiological versus conservative management and clinical outcomes[J]. J Clin Med, 2021, 10(12): 2612. PMID: 34198478. PMCID: PMC8231897. DOI: 10.3390/jcm10122612.
Angelico R, Paolantonio G, Paoletti M, et al. Combined endovascular-surgical treatment for complex congenital intrahepatic arterioportal fistula: a case report and review of the literature[J]. World J Hepatol, 2020, 12(4): 160-169. PMID: 32685108. PMCID: PMC7336291. DOI: 10.4254/wjh.v12.i4.160.
