Prevalence of diabetes mellitus among Uygur children in Hotan Prefecture of Xinjiang, China

LUO Yan-Fei, LI Jun-Kang, MAYILA·Abudoureyimu, DILIHUMA·Julaiti, REYILANMU·Baoerhan, SUN Guang-Hui, LUAN Lei-Xin, MIREGULI·Maimaiti

Chinese Journal of Contemporary Pediatrics ›› 2022, Vol. 24 ›› Issue (2) : 192-196.

PDF(546 KB)
PDF(546 KB)
Chinese Journal of Contemporary Pediatrics ›› 2022, Vol. 24 ›› Issue (2) : 192-196. DOI: 10.7499/j.issn.1008-8830.2109162
CLINICAL RESEARCH

Prevalence of diabetes mellitus among Uygur children in Hotan Prefecture of Xinjiang, China

  • LUO Yan-Fei, LI Jun-Kang, MAYILA·Abudoureyimu, DILIHUMA·Julaiti, REYILANMU·Baoerhan, SUN Guang-Hui, LUAN Lei-Xin, MIREGULI·Maimaiti
Author information +
History +

Abstract

Objective To investigate the prevalence of diabetes mellitus (DM) among Uygur children in Hotan Prefecture of Xinjiang, China, as well as the factors influencing the development of DM. Methods The cluster random sampling method was used to select 5 308 children, aged 4-18 years, from the middle and primary schools and kindergartens in Hotan Prefecture of Xinjiang. The survey methods included questionnaire survey and the measurement of height and weight. All subjects were tested for fasting fingertip blood glucose to investigate the prevalence of DM and impaired fasting glucose (IFG). Results A total of 5 184 valid questionnaires were collected. Fourteen children (0.27%) were found to have DM, among whom 8 had type 1 DM, 2 had type 2 DM, and 4 had unclassified DM. Twenty-nine children (0.56%) were found to have IFG. There was no significant difference in the prevalence rate of DM and IFG between boys and girls (P>0.05). The prevalence rate of DM was 0.18% in the 4-<10 years group, 0.47% in the 10-<15 years group, and 0.07% in the 15-18 years group (P=0.072).The prevalence rate of IFG in the above three age groups was 0.18%, 0.94%, and 0.42%, respectively, with a significant difference among groups (P=0.007). The proportion of family history of DM and the proportion of overweight/obesity in children with DM were significantly higher than those in children without DM (P<0.05), while the proportion of children with DM who preferred coarse grains was significantly lower than that in children without DM (P<0.05). Conclusions The prevalence of DM and IFG in Uyghur children in Hotan Prefecture of Xinjiang is relatively low. There is no significant difference in the prevalence of DM among children of different genders or age groups, but the prevalence of IFG in children of different age groups is different. A family history of DM, overweight or obesity, and low intake of coarse grains might be associated with the development of DM.

Key words

Diabetes mellitus / Prevalence / Impaired fasting glucose / Child

Cite this article

Download Citations
LUO Yan-Fei, LI Jun-Kang, MAYILA·Abudoureyimu, DILIHUMA·Julaiti, REYILANMU·Baoerhan, SUN Guang-Hui, LUAN Lei-Xin, MIREGULI·Maimaiti. Prevalence of diabetes mellitus among Uygur children in Hotan Prefecture of Xinjiang, China[J]. Chinese Journal of Contemporary Pediatrics. 2022, 24(2): 192-196 https://doi.org/10.7499/j.issn.1008-8830.2109162

References

1 Tuomilehto J. The emerging global epidemic of type 1 diabetes[J]. Curr Diab Rep, 2013, 13(6): 795-804. PMID: 24072479. DOI: 10.1007/s11892-013-0433-5.
2 Wu HB, Zhong JM, Hu RY, et al. Rapidly rising incidence of type 1 diabetes in children and adolescents aged 0-19 years in Zhejiang, China, 2007 to 2013[J]. Diabet Med, 2016, 33(10): 1339-1346. PMID: 26499360. DOI: 10.1111/dme.13010.
3 Zhao ZH, Sun CJ, Wang CF, et al. Rapidly rising incidence of childhood type 1 diabetes in Chinese population: epidemiology in Shanghai during 1997-2011[J]. Acta Diabetol, 2014, 51(6): 947-953. PMID: 24777734. DOI: 10.1007/s00592-014-0590-2.
4 张晶, 马依彤, 谢翔, 等. 新疆汉族、维吾尔族和哈萨克族儿童糖尿病患病率调查及相关因素分析[J]. 中华流行病学杂志, 2012, 33(11): 1130-1132. PMID: 23290897. DOI:10.3760/cma.j.issn.0254-6450.2012.11.007.
5 Wang LM, Gao P, Zhang M, et al. Prevalence and ethnic pattern of diabetes and prediabetes in China in 2013[J]. JAMA, 2017, 317(24): 2515-2523. PMID: 28655017. PMCID: PMC5815077. DOI: 10.1001/jama.2017.7596.
6 新疆维吾尔自治区统计局. 新疆维吾尔自治区2010年第六次全国人口普查主要数据公报[EB/OL]. (2011-05-16) [2018-08-14]. http://www.stats.gov.cn/tjsj/tjgb/rkpcgb/dfrkpcgb/201202/t20120228_30407.html.
7 中华医学会儿科学分会内分泌遗传代谢学组, 中华儿科杂志编辑委员会. 中国儿童1型糖尿病标准化诊断与治疗专家共识(2020版)[J]. 中华儿科杂志, 2020, 58(6): 447-454. PMID: 32521955. DOI: 10.3760/cma.j.cn112140-20200221-00124.
8 中国肥胖问题工作组. 中国学龄儿童青少年超重、肥胖筛查体重指数值分类标准[J]. 中华流行病学杂志,2004, 25(2): 97-102. DOI: 10.3760/j.issn:0254-6450.2004.02.003.
9 曹冰燕, 米杰, 巩纯秀, 等. 北京市19593名儿童青少年糖尿病患病现况调查[J]. 中华流行病学杂志, 2007, 28(7): 631-634. DOI: 10.3760/j.issn:0254-6450.2007.07.002.
10 翁建平, 周智广, 郭立新, 等. 中国2010-2013年1型糖尿病的发病率: 基于人群的研究[J]. 英国医学杂志中文版, 2019, 22(9): 509-517.
11 Park Y, Wintergerst KA, Zhou ZG. Clinical heterogeneity of type 1 diabetes (T1D) found in Asia[J]. Diabetes Metab Res Rev, 2017, 33(7): e2907. PMID: 28544229. DOI: 10.1002/dmrr.2907.
12 Wei GS, Coady SA, Goff DCJ, et al. Blood pressure and the risk of developing diabetes in African Americans and whites: ARIC, CARDIA, and the Framingham heart study[J]. Diabetes Care, 2011, 34(4): 873-879. PMID: 21346180. PMCID: PMC3064044. DOI: 10.2337/dc10-1786.
13 Tandon N. Understanding type 1 diabetes through genetics: advances and prospects[J]. Indian J Endocrinol Metab, 2015, 19(Suppl 1): S39-S43. PMID: 25941648. PMCID: PMC4413387. DOI: 10.4103/2230-8210.155391.
14 郑朝安, 傅君芬, 董关萍. 1型糖尿病的发病机制[J]. 国际儿科学杂志, 2020, 47(4): 274-278. DOI: 10.3760/cma.j.issn.1673-4408.2020.04.014.
15 Chen Y, Zhang XP, Yuan J, et al. Association of body mass index and age with incident diabetes in Chinese adults: a population-based cohort study[J]. BMJ Open, 2018, 8(9): e021768. PMID: 30269064. PMCID: PMC6169758. DOI: 10.1136/bmjopen-2018-021768.
16 冯海霞, 万燕萍, 周一泉, 等. 儿童单纯性肥胖相关危险因素的性别差异[J]. 中华实用儿科临床杂志, 2014, 29(19): 1471-1475. DOI: 10.3760/j.issn.2095-428X.2014.19.009.
17 Ji CY, Chen TJ, Working Group on Obesity in China (WGOC). Empirical changes in the prevalence of overweight and obesity among Chinese students from 1985 to 2010 and corresponding preventive strategies[J]. Biomed Environ Sci, 2013, 26(1): 1-12. PMID: 23294610. DOI: 10.3967/0895-3988.2013.01.001.
18 马冠生. 中国儿童肥胖报告[M]. 北京: 人民卫生出版社, 2017.
19 Steyn NP, Mann J, Bennett PH, et al. Diet, nutrition and the prevention of type 2 diabetes[J]. Public Health Nutr, 2004, 7(1A): 147-165. PMID: 14972058. DOI: 10.1079/phn2003586.
20 殷峻. 从胰腺切除术后的糖尿病和节俭基因假说谈低碳饮食对糖尿病的防治[J]. 中华糖尿病杂志, 2019, 11(8): 513-517. DOI: 10.3760/cma.j.issn.1674-5809.2019.08.003.
21 Sinau S, Montaunier C, Wils D, et al. Net energy value of two low-digestible carbohydrates, Lycasin HBC and the hydrogenated polysaccharide fraction of Lycasin HBC in healthy human subjects and their impact on nutrient digestive utilization[J]. Br J Nutr, 2002, 87(2): 131-139. PMID: 11895165. DOI: 10.1079/bjn2001491.
22 何凤怡, 陈超刚, 林刁珠, 等. 膳食纤维和血糖负荷与糖代谢异常风险的相关性[J]. 中华内分泌代谢杂志, 2016, 32(1): 38-41. DOI: 10.3760/cma.j.issn.1000-6699.2016.01.010.
PDF(546 KB)

Accesses

Citation

Detail

Sections
Recommended

/