Outcome of neonates born to mothers with chronic kidney disease

XU Zhao-Jie; LUO Fang

doi:10.7499/j.issn.1008-8830.2207017

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Chinese Journal of Contemporary Pediatrics ›› 2023, Vol. 25 ›› Issue (1) : 104-108. DOI: 10.7499/j.issn.1008-8830.2207017

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Outcome of neonates born to mothers with chronic kidney disease

XU Zhao-Jie, LUO Fang

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Abstract

About 3% of pregnant women suffer from chronic kidney disease (CKD). This article reviews the literature on the outcomes of neonates born to mothers with CKD (including those undergoing dialysis and kidney transplantation), and the results show that CKD during pregnancy may increase the risk of preterm birth, low birth weight, and small for gestational age infant, but it does not increase the risk of congenital anomalies. As for long-term outcomes, CKD during pregnancy has no significant impact on offspring's physical development and immune function. Neurodevelopmental outcome of offspring is associated with preterm birth and low birth weight, rather than intrauterine drug exposure. However, further research and follow-up are needed to investigate the outcome of neonates born to mothers with CKD.

Key words

Chronic kidney disease / Dialysis / Kidney transplantation / Pregnancy outcome / Neonate

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XU Zhao-Jie, LUO Fang. Outcome of neonates born to mothers with chronic kidney disease[J]. Chinese Journal of Contemporary Pediatrics. 2023, 25(1): 104-108 https://doi.org/10.7499/j.issn.1008-8830.2207017

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