Recent research on the association between depressive disorder and gene polymorphisms in adolescents

YAO Ke-Ke; DONG Qiang-Li; YE Lan-Xian

doi:10.7499/j.issn.1008-8830.2208178

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Chinese Journal of Contemporary Pediatrics ›› 2023, Vol. 25 ›› Issue (3) : 328-332. DOI: 10.7499/j.issn.1008-8830.2208178

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Recent research on the association between depressive disorder and gene polymorphisms in adolescents

YAO Ke-Ke, DONG Qiang-Li, YE Lan-Xian

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Abstract

Biogenetics plays an important role in the pathogenesis of depressive disorder in adolescents. Various genetic polymorphism studies have updated the understanding of adolescent depressive disorder. However, due to the influence of gene-environment interaction and age of puberty, the influence of gene polymorphisms on adolescent depressive disorder is complicated to clarify. Investigating and clarifying the relationship between gene polymorphisms and adolescent depressive disorder will promote the research on the pathogenesis of this disorder and provide a reference for the prevention and treatment of this disorder. This article reviews the genetic polymorphisms related to adolescent depressive disorder.

Key words

Depressive disorder / Gene polymorphism / Adolescent

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YAO Ke-Ke, DONG Qiang-Li, YE Lan-Xian. Recent research on the association between depressive disorder and gene polymorphisms in adolescents[J]. Chinese Journal of Contemporary Pediatrics. 2023, 25(3): 328-332 https://doi.org/10.7499/j.issn.1008-8830.2208178

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