Advancements in the diagnosis and treatment of pediatric acute liver failure

MING Hui; HE Yi; XU Hong-Mei

doi:10.7499/j.issn.1008-8830.2309015

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Chinese Journal of Contemporary Pediatrics ›› 2024, Vol. 26 ›› Issue (2) : 194-200. DOI: 10.7499/j.issn.1008-8830.2309015

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Advancements in the diagnosis and treatment of pediatric acute liver failure

MING Hui, HE Yi, XU Hong-Mei

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Abstract

Pediatric acute liver failure (PALF) is a rare and rapidly progressive clinical syndrome with a poor prognosis and significant mortality. The etiology of PALF is complex, and it presents with diverse and atypical clinical manifestations. Accurate diagnosis based on age-related factors, early recognition or prevention of hepatic encephalopathy, and precise supportive treatment targeting the underlying cause are crucial for improving outcomes and prognosis. This article provides a comprehensive review of recent research on the diagnosis and treatment of PALF, aiming to offer guidance for clinical practice.

Key words

Acute liver failure / Diagnosis / Treatment / Child

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MING Hui, HE Yi, XU Hong-Mei. Advancements in the diagnosis and treatment of pediatric acute liver failure[J]. Chinese Journal of Contemporary Pediatrics. 2024, 26(2): 194-200 https://doi.org/10.7499/j.issn.1008-8830.2309015

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