Control status and follow-up of acute attacks in children with bronchial asthma with normal pulmonary ventilation function

MA Lan-Lan, CHEN Ling, WANG Qin, XU Yang-Guang, CHEN Xing

Chinese Journal of Contemporary Pediatrics ›› 2024, Vol. 26 ›› Issue (5) : 476-480.

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Chinese Journal of Contemporary Pediatrics ›› 2024, Vol. 26 ›› Issue (5) : 476-480. DOI: 10.7499/j.issn.1008-8830.2311149
CLINICAL RESEARCH

Control status and follow-up of acute attacks in children with bronchial asthma with normal pulmonary ventilation function

  • MA Lan-Lan, CHEN Ling, WANG Qin, XU Yang-Guang, CHEN Xing
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Abstract

Objective To investigate the control status of bronchial asthma (referred to as "asthma") in school-age children with normal pulmonary ventilation function and the occurrence of acute attacks within 1 year of follow-up. Methods A retrospective analysis was conducted on clinical data of 327 children aged 6-14 years with bronchial asthma and normal pulmonary ventilation function from April to September 2021. Based on the measured value of one second rate (FEV1/FVC), the children were divided into the ≥80% group (267 cases) and the <80% group (60 cases). The pulmonary ventilation function, asthma control level, and occurrence of acute attacks within 1 year were compared between the two groups. Results The baseline pulmonary ventilation function in the <80% group was lower than that in the ≥80% group, and the proportion of small airway dysfunction was higher than that in the ≥80% group (P<0.05). After standardized treatment for 1 year, the small airway function indices in the <80% group improved but remained lower than those in the ≥80% group (P<0.05). The rate of incomplete asthma control at baseline was 34.6% (113/327), and the asthma control level in the <80% group was lower than that in the ≥80% group (P<0.05). After standardized treatment for 1 year, the asthma control level in the <80% group remained lower than that in the ≥80% group, and the proportion of acute asthma attacks was higher than that in the ≥80% group (P<0.05). Conclusions Approximately one-third of school-age children with asthma still have incomplete asthma control when their pulmonary ventilation function is normal. Among them, children with measured FEV1/FVC<80% have an increased risk of acute asthma attacks and require close follow-up and strengthened asthma management.

Key words

Bronchial asthma / Pulmonary ventilatory function / Asthma control / Child

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MA Lan-Lan, CHEN Ling, WANG Qin, XU Yang-Guang, CHEN Xing. Control status and follow-up of acute attacks in children with bronchial asthma with normal pulmonary ventilation function[J]. Chinese Journal of Contemporary Pediatrics. 2024, 26(5): 476-480 https://doi.org/10.7499/j.issn.1008-8830.2311149

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