Recommendations for antibiotic use in hospitalized preterm infants with late-onset sepsis in the neonatal intensive care unit

Hunan Neonatal Medical Quality Control Center; Neonatology Group of Perinatal Medical Committee of Hunan Medical Association

doi:10.7499/j.issn.1008-8830.2408024

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Chinese Journal of Contemporary Pediatrics ›› 2024, Vol. 26 ›› Issue (10) : 1009-1018. DOI: 10.7499/j.issn.1008-8830.2408024

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Recommendations for antibiotic use in hospitalized preterm infants with late-onset sepsis in the neonatal intensive care unit

Hunan Neonatal Medical Quality Control Center; Neonatology Group of Perinatal Medical Committee of Hunan Medical Association

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Abstract

Late-onset sepsis (LOS) is commonly seen in neonates who are hospitalized for extended periods, particularly in very low birth weight infants (VLBWI) and extremely low birth weight infants (ELBWI). Currently, the management of LOS in preterm infants faces dual challenges of delayed diagnosis and treatment, as well as antibiotic overtreatment. To address these issues, the Hunan Neonatal Medical Quality Control Center and the Neonatology Group of Perinatal Medical Committee of Hunan Medical Association organized a group of neonatal experts from Hunan Province to formulate recommendations based on published literature and statistical data from the Hunan Neonatal Medical Quality Control Center, as well as real-world practices in most neonatal intensive care units in Hunan Province. The group of neonatal experts proposed 15 recommendations for the diagnosis and antibiotic treatment of LOS in hospitalized preterm infants in the neonatal intensive care unit.

Key words

Late-onset sepsis / Neonatal intensive care unit / Antibiotic / Recommendation / Preterm infant

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Hunan Neonatal Medical Quality Control Center; Neonatology Group of Perinatal Medical Committee of Hunan Medical Association. Recommendations for antibiotic use in hospitalized preterm infants with late-onset sepsis in the neonatal intensive care unit[J]. Chinese Journal of Contemporary Pediatrics. 2024, 26(10): 1009-1018 https://doi.org/10.7499/j.issn.1008-8830.2408024

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