Research progress on the relationship between gut microbiota and childhood bronchial asthma

Lei YU; Mao-Lan WU; Xiang-Rong ZHENG

doi:10.7499/j.issn.1008-8830.2411113

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Chinese Journal of Contemporary Pediatrics ›› 2025, Vol. 27 ›› Issue (5) : 623-628. DOI: 10.7499/j.issn.1008-8830.2411113

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Research progress on the relationship between gut microbiota and childhood bronchial asthma

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Abstract

Bronchial asthma (asthma) is a complex inflammatory airway disease affecting approximately 100 million children worldwide, imposing a heavy burden on society and families. Studies have shown that the gut microbiota plays a significant role in the occurrence and development of childhood asthma. This paper reviews the research progress on the relationship between gut microbiota and childhood asthma. By elucidating the composition, function, and relationship with the host of gut microbiota, the impact of changes in its composition and function on the development of asthma is revealed. Furthermore, the potential value and application prospects of modulating gut microbiota as a new strategy for asthma treatment are discussed, providing a theoretical reference for in-depth research on the relationship between gut microbiota and the onset of childhood asthma and the development of new therapeutic approaches.

Key words

Bronchial asthma / Gut microbiota / Pathogenesis / Treatment / Child

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Lei YU , Mao-Lan WU , Xiang-Rong ZHENG. Research progress on the relationship between gut microbiota and childhood bronchial asthma[J]. Chinese Journal of Contemporary Pediatrics. 2025, 27(5): 623-628 https://doi.org/10.7499/j.issn.1008-8830.2411113

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