[1]	Khan AM, Morris SK, Bhutta ZA. Neonatal and perinatal infections[J]. Pediatr Clin North Am, 2017, 64(4): 785-798. DOI: 10.1016/j.pcl.2017.03.008 . https://www.ncbi.nlm.nih.gov/pubmed/28734510 Cited in this article [1]

[2]	Fleischmann-Struzek C, Goldfarb DM, Schlattmann P, et al. The global burden of paediatric and neonatal sepsis: a systematic review[J]. Lancet Respir Med, 2018, 6(3): 223-230. DOI: 10.1016/S2213-2600(18)30063-8 . https://www.ncbi.nlm.nih.gov/pubmed/29508706 Cited in this article [1]

[3]	中华医学会儿科学分会新生儿学组, 中华医学会中华儿科杂志编辑委员会. 新生儿败血症诊疗方案[J]. 中华儿科杂志, 2003, 41(12): 897-899. DOI: 10.3760/j.issn:0578-1310.2003.12.005 . https://www.ncbi.nlm.nih.gov/pubmed/14723808 Cited in this article [1]

[4]	中华医学会儿科学分会新生儿学组, 中国医师协会新生儿科医师分会感染专业委员会. 新生儿败血症诊断及治疗专家共识（2019年版）[J]. 中华儿科杂志, 2019, 57(4): 252-257. DOI: 10.3760/cma.j.issn.0578-1310.2019.04.005 . https://www.ncbi.nlm.nih.gov/pubmed/30934196 Cited in this article [1]

[5]	Puopolo KM, Benitz WE, Zaoutis TE, et al. Management of neonates born at ≥35 0/7 weeks' gestation with suspected or proven early-onset bacterial sepsis[J]. Pediatrics, 2018, 142(6): e20182894. DOI: 10.1542/peds.2018-2894 . https://www.ncbi.nlm.nih.gov/pubmed/30455342 Cited in this article [4]

[6]	NICE. Neonatal infection (early onset): antibiotics for prevention and treatment[EB/OL]. (2012-08-22)[2024-08-15]. https://www.nice.org.uk/guidance/cg149

[7]	NICE. Neonatal infection: antibiotics for prevention and treatment[EB/OL]. (2024-03-19)[2024-08-15]. https://www.nice.org.uk/guidance/ng195 Cited in this article [7]

[8]	Puopolo KM, Benitz WE, Zaoutis TE, et al. Management of neonates born at ≤34 6/7 weeks' gestation with suspected or proven early-onset bacterial sepsis[J]. Pediatrics, 2018, 142(6): e20182896. DOI: 10.1542/peds.2018-2896 . https://www.ncbi.nlm.nih.gov/pubmed/30455344 Cited in this article [5]

[9]	Dong R, Liu W, Weng L, et al. Temporal trends of sepsis-related mortality in China, 2006-2020: a population-based study[J]. Ann Intensive Care, 2023, 13(1): 71. PMCID: PMC10425320. DOI: 10.1186/s13613-023-01166-1 . https://www.ncbi.nlm.nih.gov/pubmed/37578609 Cited in this article [1]

[10]	中华医学会儿科学分会新生儿学组, 中华儿科杂志编辑委员会. 新生儿败血症诊断与治疗专家共识（2024）[J]. 中华儿科杂志, 2024, 62(10): 931-940. DOI: 10.3760/cma.j.cn112140-20240505-00307 . https://www.ncbi.nlm.nih.gov/pubmed/39327959 Cited in this article [4]

[11]	Polin RA; Committee on Fetus and Newborn. Management of neonates with suspected or proven early-onset bacterial sepsis[J]. Pediatrics, 2012, 129(5): 1006-1015. DOI: 10.1542/peds.2012-0541 . https://www.ncbi.nlm.nih.gov/pubmed/22547779 Cited in this article [2]

[12]	Committee Opinion No. 712: intrapartum management of intraamniotic infection[J]. Obstet Gynecol, 2017, 130(2): e95-e101. DOI: 10.1097/AOG.0000000000002236 . https://www.ncbi.nlm.nih.gov/pubmed/28742677 Cited in this article [1]

[13]

Higgins RD, Saade G, Polin RA, et al. Evaluation and management of women and newborns with a maternal diagnosis of chorioamnionitis: summary of a workshop[J]. Obstet Gynecol, 2016, 127(3): 426-436. PMCID: PMC4764452. DOI: 10.1097/AOG.0000000000001246 . https://www.ncbi.nlm.nih.gov/pubmed/26855098 Cited in this article [3]

[14]	Strunk T, Doherty D, Jacques A, et al. Histologic chorioamnionitis is associated with reduced risk of late-onset sepsis in preterm infants[J]. Pediatrics, 2012, 129(1): e134-e141. DOI: 10.1542/peds.2010-3493 . https://www.ncbi.nlm.nih.gov/pubmed/22157134 Cited in this article [1]

[15]	Coggins SA, Glaser K. Updates in late-onset sepsis: risk assessment, therapy, and outcomes[J]. Neoreviews, 2022, 23(11): 738-755. PMCID: PMC9675597. DOI: 10.1542/neo.23-10-e738 . https://www.ncbi.nlm.nih.gov/pubmed/36316254 Cited in this article [1]

[16]

Köstlin-Gille N, Härtel C, Haug C, et al. Epidemiology of early and late onset neonatal sepsis in very low birthweight infants: data from the German neonatal network[J]. Pediatr Infect Dis J, 2021, 40(3): 255-259. DOI: 10.1097/INF.0000000000002976 . https://www.ncbi.nlm.nih.gov/pubmed/33538544 Cited in this article [1]

[17]	Shah J, Jefferies AL, Yoon EW, et al. Risk factors and outcomes of late-onset bacterial sepsis in preterm neonates born at < 32 weeks' gestation[J]. Am J Perinatol, 2015, 32(7): 675-682. DOI: 10.1055/s-0034-1393936 . https://www.ncbi.nlm.nih.gov/pubmed/25486288 Cited in this article [1]

[18]	Tsai MH, Hsu JF, Chu SM, et al. Incidence, clinical characteristics and risk factors for adverse outcome in neonates with late-onset sepsis[J]. Pediatr Infect Dis J, 2014, 33(1): e7-e13. DOI: 10.1097/INF.0b013e3182a72ee0 . https://www.ncbi.nlm.nih.gov/pubmed/23899966 Cited in this article [1]

[19]

Shen R, Embleton N, Lyng Forman J, et al. Early antibiotic use and incidence of necrotising enterocolitis in very preterm infants: a protocol for a UK based observational study using routinely recorded data[J]. BMJ Open, 2022, 12(11): e065934. PMCID: PMC9667987. DOI: 10.1136/bmjopen-2022-065934 . https://www.ncbi.nlm.nih.gov/pubmed/36379645 Cited in this article [1]

[20]

Kuppala VS, Meinzen-Derr J, Morrow AL, et al. Prolonged initial empirical antibiotic treatment is associated with adverse outcomes in premature infants[J]. J Pediatr, 2011, 159(5): 720-725. PMCID: PMC3193552. DOI: 10.1016/j.jpeds.2011.05.033 . https://www.ncbi.nlm.nih.gov/pubmed/21784435 Cited in this article [1]

[21]	贺雨, 史源. 2021年新生儿感染: 抗菌药物预防性与治疗性使用指南解读[J]. 中华儿科杂志, 2022, 60(2): 84-87. DOI: 10.3760/cma.j.cn112140-20211025-00903 . https://www.ncbi.nlm.nih.gov/pubmed/35090222 Cited in this article [2]

[22]

Barug D, Goorden S, Herruer M, et al. Reference values for interleukin-6 and interleukin-8 in cord blood of healthy term neonates and their association with stress-related perinatal factors[J]. PLoS One, 2014, 9(12): e114109. PMCID: PMC4259323. DOI: 10.1371/journal.pone.0114109 . https://www.ncbi.nlm.nih.gov/pubmed/25485809 Cited in this article [1]

[23]	Cortés JS, Losada PX, Fernández LX, et al. Interleukin-6 as a biomarker of early-onset neonatal sepsis[J]. Am J Perinatol, 2021, 38(S 01): e338-e346. DOI: 10.1055/s-0040-1710010 . https://www.ncbi.nlm.nih.gov/pubmed/32446256

[24]	Xing W, Wang Y, Liu J, et al. Role of interleukins in the detection of neonatal sepsis: a network meta-analysis[J]. Front Pediatr, 2023, 11: 1267777. PMCID: PMC10652565. DOI: 10.3389/fped.2023.1267777 . https://www.ncbi.nlm.nih.gov/pubmed/38027268 Cited in this article [1]

[25]	郝盈夏, 余加林. 白细胞计数对新生儿早发型败血症的诊断界值探讨[J]. 中国当代儿科杂志, 2020, 22(11): 1159-1163. PMCID: PMC7666395. DOI: 10.7499/j.issn.1008-8830.2005143 . https://www.ncbi.nlm.nih.gov/pubmed/33172548 Cited in this article [1]

[26]	Sharma D, Farahbakhsh N, Shastri S, et al. Biomarkers for diagnosis of neonatal sepsis: a literature review[J]. J Matern Fetal Neonatal Med, 2018, 31(12): 1646-1659. DOI: 10.1080/14767058.2017.1322060 . https://www.ncbi.nlm.nih.gov/pubmed/28427289 Cited in this article [2]

[27]	Lloyd BW, Oto A. Normal values for mature and immature neutrophils in very preterm babies[J]. Arch Dis Child, 1982, 57(3): 233-235. PMCID: PMC1627598. DOI: 10.1136/adc.57.3.233 . https://www.ncbi.nlm.nih.gov/pubmed/7073305 Cited in this article [1]

[28]	Manzoni P, Mostert M, Galletto P, et al. Is thrombocytopenia suggestive of organism-specific response in neonatal sepsis?[J]. Pediatr Int, 2009, 51(2): 206-210. DOI: 10.1111/j.1442-200X.2008.02689.x . https://www.ncbi.nlm.nih.gov/pubmed/19405917 Cited in this article [2]

[29]	中华医学会儿科学分会医院感染管理与控制专业委员会. 血清降钙素原检测在儿童感染性疾病中的临床应用专家共识[J]. 中华儿科杂志, 2019, 57(1): 9-15. DOI: 10.3760/cma.j.issn.0578-1310.2019.01.005 . https://www.ncbi.nlm.nih.gov/pubmed/30630225 Cited in this article [1]

[30]	Reinhart K, Bauer M, Riedemann NC, et al. New approaches to sepsis: molecular diagnostics and biomarkers[J]. Clin Microbiol Rev, 2012, 25(4): 609-634. PMCID:PMC3485751. DOI: 10.1128/CMR.00016-12 . https://www.ncbi.nlm.nih.gov/pubmed/23034322 Cited in this article [2]

[31]	Benitz WE, Wynn JL, Polin RA. Reappraisal of guidelines for management of neonates with suspected early-onset sepsis[J]. J Pediatr, 2015, 166(4): 1070-1074. PMCID: PMC4767008. DOI: 10.1016/j.jpeds.2014.12.023 . https://www.ncbi.nlm.nih.gov/pubmed/25641240 Cited in this article [1]

[32]	Mjelle AB, Guthe HJT, Reigstad H, et al. Serum concentrations of C-reactive protein in healthy term-born Norwegian infants 48-72 hours after birth[J]. Acta Paediatr, 2019, 108(5): 849-854. DOI: 10.1111/apa.14578 . https://www.ncbi.nlm.nih.gov/pubmed/30222898 Cited in this article [1]

[33]	Perrone S, Lotti F, Longini M, et al. C reactive protein in healthy term newborns during the first 48 hours of life[J]. Arch Dis Child Fetal Neonatal Ed, 2018, 103(2): F163-F166. DOI: 10.1136/archdischild-2016-312506 . https://www.ncbi.nlm.nih.gov/pubmed/28667188 Cited in this article [1]

[34]	Schlapbach LJ, Graf R, Woerner A, et al. Pancreatic stone protein as a novel marker for neonatal sepsis[J]. Intensive Care Med, 2013, 39(4): 754-763. DOI: 10.1007/s00134-012-2798-3 . https://www.ncbi.nlm.nih.gov/pubmed/23296629 Cited in this article [1]

[35]

Isaacs D, Barfield CP, Grimwood K, et al. Systemic bacterial and fungal infections in infants in Australian neonatal units. Australian study group for neonatal infections[J]. Med J Aust, 1995, 162(4): 198-201. DOI: 10.5694/j.1326-5377.1995.tb126024.x . https://www.ncbi.nlm.nih.gov/pubmed/7877542 Cited in this article [1]

[36]	Deisenhammer F, Bartos A, Egg R, et al. Guidelines on routine cerebrospinal fluid analysis. Report from an EFNS task force[J]. Eur J Neurol, 2006, 13(9): 913-922. DOI: 10.1111/j.1468-1331.2006.01493.x . https://www.ncbi.nlm.nih.gov/pubmed/16930354 Cited in this article [1]

[37]

Garges HP, Moody MA, Cotten CM, et al. Neonatal meningitis: what is the correlation among cerebrospinal fluid cultures, blood cultures, and cerebrospinal fluid parameters?[J]. Pediatrics, 2006, 117(4): 1094-1100. DOI: 10.1542/peds.2005-1132 . https://www.ncbi.nlm.nih.gov/pubmed/16585303 Cited in this article [1]

[38]	Mhanna MJ, Alesseh H, Gori A, et al. Cerebrospinal fluid values in very low birth weight infants with suspected sepsis at different ages[J]. Pediatr Crit Care Med, 2008, 9(3): 294-298. DOI: 10.1097/01.PCC.0b013e31816c6e12 . https://www.ncbi.nlm.nih.gov/pubmed/18446114 Cited in this article [1]

[39]	Zimmermann P, Curtis N. Normal values for cerebrospinal fluid in neonates: a systematic review[J]. Neonatology, 2021, 118(6): 629-638. DOI: 10.1159/000517630 . https://www.ncbi.nlm.nih.gov/pubmed/34818234 Cited in this article [1]

[40]	Flidel-Rimon O, Galstyan S, Juster-Reicher A, et al. Limitations of the risk factor based approach in early neonatal sepsis evaluations[J]. Acta Paediatr, 2012, 101(12): e540-e544. DOI: 10.1111/apa.12013 . https://www.ncbi.nlm.nih.gov/pubmed/22937988 Cited in this article [1]

[41]

Mukhopadhyay S, Eichenwald EC, Puopolo KM. Neonatal early-onset sepsis evaluations among well-appearing infants: projected impact of changes in CDC GBS guidelines[J]. J Perinatol, 2013, 33(3): 198-205. PMCID: PMC3782314. DOI: 10.1038/jp.2012.96 . https://www.ncbi.nlm.nih.gov/pubmed/22814941 Cited in this article [1]

[42]	中国妇幼保健协会新生儿保健专业委员会, 中国医师协会新生儿科医师分会. 母婴同室早发感染高危新生儿临床管理专家共识[J]. 中华围产医学杂志, 2021, 24(8): 567-575. DOI: 10.3760/cma.j.cn113903-20210310-00202 . Cited in this article [2]

[43]

Cantey JB, Wozniak PS, Pruszynski JE, et al. Reducing unnecessary antibiotic use in the neonatal intensive care unit (SCOUT): a prospective interrupted time-series study[J]. Lancet Infect Dis, 2016, 16(10): 1178-1184. DOI: 10.1016/S1473-3099(16)30205-5 . https://www.ncbi.nlm.nih.gov/pubmed/27452782 Cited in this article [1]

[44]	Korang SK, Safi S, Nava C, et al. Antibiotic regimens for early-onset neonatal sepsis[J]. Cochrane Database Syst Rev, 2021, 5(5): CD013837. PMCID: PMC8127574. DOI: 10.1002/14651858.CD013837.pub2 . https://www.ncbi.nlm.nih.gov/pubmed/33998666 Cited in this article [1]

[45]	Zhang J, Folgori L, Hsia Y, et al. Pattern of antimicrobial resistance in bloodstream isolates from Chinese neonates[J]. Pediatr Infect Dis J, 2019, 38(6): 600-604. DOI: 10.1097/INF.0000000000002246 . https://www.ncbi.nlm.nih.gov/pubmed/30672894 Cited in this article [2]

[46]

Harrison ML, Dickson BFR, Sharland M, et al. Beyond early- and late-onset neonatal sepsis definitions: what are the current causes of neonatal sepsis globally? A systematic review and meta-analysis of the evidence[J]. Pediatr Infect Dis J, 2024, 43(12): 1182-1190. PMCID: PMC11542974. DOI: 10.1097/INF.0000000000004485 . https://www.ncbi.nlm.nih.gov/pubmed/39264197 Cited in this article [2]

[47]

Giannoni E, Agyeman PKA, Stocker M, et al. Neonatal sepsis of early onset, and hospital-acquired and community-acquired late onset: a prospective population-based cohort study[J]. J Pediatr, 2018, 201: 106-114.e4. DOI: 10.1016/j.jpeds.2018.05.048 . https://www.ncbi.nlm.nih.gov/pubmed/30054165 Cited in this article [1]

[48]	Pan T, Zhu Q, Li P, et al. Late-onset neonatal sepsis in Suzhou, China[J]. BMC Pediatr, 2020, 20(1): 261. PMCID: PMC7257513. DOI: 10.1186/s12887-020-02103-y . https://www.ncbi.nlm.nih.gov/pubmed/32471377 Cited in this article [1]

[49]

Qiu Y, Yang J, Chen Y, et al. Microbiological profiles and antimicrobial resistance patterns of pediatric bloodstream pathogens in China, 2016-2018[J]. Eur J Clin Microbiol Infect Dis, 2021, 40(4): 739-749. DOI: 10.1007/s10096-020-04069-2 . https://www.ncbi.nlm.nih.gov/pubmed/33078219 Cited in this article [1]

[50]

Ting JY, Autmizguine J, Dunn MS, et al. Practice summary of antimicrobial therapy for commonly encountered conditions in the neonatal intensive care unit: a Canadian perspective[J]. Front Pediatr, 2022, 10: 894005. PMCID: PMC9304938. DOI: 10.3389/fped.2022.894005 . https://www.ncbi.nlm.nih.gov/pubmed/35874568 Cited in this article [1]

[51]	Ouchenir L, Renaud C, Khan S, et al. The epidemiology, management, and outcomes of bacterial meningitis in infants[J]. Pediatrics, 2017, 140(1): e20170476. DOI: 10.1542/peds.2017-0476 . https://www.ncbi.nlm.nih.gov/pubmed/28600447 Cited in this article [2]

[52]

Tunkel AR, Hasbun R, Bhimraj A, et al. 2017 Infectious Diseases Society of America's clinical practice guidelines for healthcare-associated ventriculitis and meningitis[J]. Clin Infect Dis, 2017, 64(6): e34-e65. PMCID: PMC5848239. DOI: 10.1093/cid/ciw861 . https://www.ncbi.nlm.nih.gov/pubmed/28203777 Cited in this article [2]

[53]	中国医师协会神经外科医师分会神经重症专家委员会, 北京医学会神经外科学分会神经外科危重症学组. 神经外科中枢神经系统感染诊治中国专家共识（2021版）[J]. 中华神经外科杂志, 2021, 37(1): 2-15. DOI: 10.3760/cma.j.cn112050-20200831-00480 . Cited in this article [1]

[54]	Heath PT, Okike IO, Oeser C. Neonatal meningitis: can we do better?[J]. Adv Exp Med Biol, 2011, 719: 11-24. DOI: 10.1007/978-1-4614-0204-6_2 . https://www.ncbi.nlm.nih.gov/pubmed/22125031 Cited in this article [2]

[55]	Greenberg RG, Benjamin DK, Cohen-Wolkowiez M, et al. Repeat lumbar punctures in infants with meningitis in the neonatal intensive care unit[J]. J Perinatol, 2011, 31(6): 425-429. PMCID: PMC3103623. DOI: 10.1038/jp.2010.142 . https://www.ncbi.nlm.nih.gov/pubmed/21164430 Cited in this article [1]

[56]	Heath PT, Nik Yusoff NK, Baker CJ. Neonatal meningitis[J]. Arch Dis Child Fetal Neonatal Ed, 2003, 88(3): F173-F178. PMCID: PMC1721548. DOI: 10.1136/fn.88.3.f173 . https://www.ncbi.nlm.nih.gov/pubmed/12719388 Cited in this article [1]

[57]	Pong A, Bradley JS. Bacterial meningitis and the newborn infant[J]. Infect Dis Clin North Am, 1999, 13(3): 711-733. DOI: 10.1016/S0891-5520(05)70102-1 . https://www.ncbi.nlm.nih.gov/pubmed/10470563 Cited in this article [1]

[58]

Ge M, Gan M, Yan K, et al. Combining metagenomic sequencing with whole exome sequencing to optimize clinical strategies in neonates with a suspected central nervous system infection[J]. Front Cell Infect Microbiol, 2021, 11: 671109. PMCID: PMC8253254. DOI: 10.3389/fcimb.2021.671109 . https://www.ncbi.nlm.nih.gov/pubmed/34222042 Cited in this article [1]

[59]	Nickerson JP, Richner B, Santy K, et al. Neuroimaging of pediatric intracranial infection—part 1: techniques and bacterial infections[J]. J Neuroimaging, 2012, 22(2): e42-e51. DOI: 10.1111/j.1552-6569.2011.00700.x . https://www.ncbi.nlm.nih.gov/pubmed/22304299 Cited in this article [1]

[60]	Gaschignard J, Levy C, Bingen E, et al. Epidemiology of Escherichia coli neonatal meningitis[J]. Arch Pediatr, 2012, 19 : S129-S134. DOI: 10.1016/S0929-693X(12)71286-1 . https://www.ncbi.nlm.nih.gov/pubmed/23178134 Cited in this article [1] Abstract Suppl 3

[61]	曹云. 新生儿感染性休克的诊治进展[J]. 中国当代儿科杂志, 2017, 19(2): 129-136. PMCID: PMC7389477. DOI: 10.7499/j.issn.1008-8830.2017.02.001 . https://www.ncbi.nlm.nih.gov/pubmed/28202107 Cited in this article [1]