Colonoscopy in infants: procedure and disease spectrum analysis of 184 cases

Xiao-Li FU; Xu-Xia WEI; Jun-Jie XU; Ning XUE; Hong-Ling CHEN; Le ZHANG

doi:10.7499/j.issn.1008-8830.2502085

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Chinese Journal of Contemporary Pediatrics ›› 2025, Vol. 27 ›› Issue (8) : 917-922. DOI: 10.7499/j.issn.1008-8830.2502085

CLINICAL RESEARCH

Colonoscopy in infants: procedure and disease spectrum analysis of 184 cases

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Abstract

Objective To investigate the underlying causes and clinical manifestations in infants undergoing colonoscopy, and to analyze changes in disease spectrum. Methods Clinical data from 180 infants who underwent a total of 184 colonoscopies at the Department of Gastroenterology, Children's Hospital Affiliated to Shandong University from January 2015 to December 2024 were retrospectively analyzed. Patients were grouped by age: ≤6 months (n=41) and >6-12 months (n=139); and by examination period: 2015-2019 (n=83) and 2020-2024 (n=97). Primary causes for performing colonoscopy, final diagnoses, and disease spectrum evolution were assessed. Results Among 184 colonoscopies, the leading causes prompting examination were hematochezia (37.8%, 68/180), diarrhea (36.7%, 66/180), and co-occurring hematochezia and diarrhea (21.1%, 38/180). Causes for performing colonoscopy differed significantly by age group (P<0.05). Colonic polyps were only detected in the >6-12 months group (P<0.05). Compared to the 2015-2019 group, the 2020-2024 group had fewer food allergy-related gastrointestinal diseases (P<0.05) but more colitis (P<0.05). Conclusions Colonoscopy is essential for diagnosing infantile digestive disorders, with disease spectra varying by age and time period.

Key words

Infantile-onset inflammatory bowel disease / Polyp / Colonoscopy / Disease spectrum / Infant

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Xiao-Li FU , Xu-Xia WEI , Jun-Jie XU , et al . Colonoscopy in infants: procedure and disease spectrum analysis of 184 cases[J]. Chinese Journal of Contemporary Pediatrics. 2025, 27(8): 917-922 https://doi.org/10.7499/j.issn.1008-8830.2502085

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