Objective To investigate the clinical features, treatment and prognosis of vesicoureteric reflux (VUR) in children. Methods Fifty eight cases of children with VUR were enrolled in this retrospective study. Results Primary VUR accounted for 53% and secondary VUR account for 47% . VUR was likely to occurr in children under three years, and the clinical symptoms of VUR were non specific in most patients. The more serious the reflux, the more likely the scarring. The severity of proteinuria and hypertension was directly associated with the reduction of renal function. Persistent small doses of antibiotics were used as preventive therapy; this was successful in 71% of the cases of VUR. Conclusions Early diagnosis and immediate treatment are necessary to improve the prognosis of VUR.