
Clinical Pathology and Long Term Prognosis of HenochSchonlein Nephritis in Children
ZHOU Ling, CHEN Zhong, JIA Qu
Chinese Journal of Contemporary Pediatrics ›› 2001, Vol. 3 ›› Issue (2) : 139-140.
Clinical Pathology and Long Term Prognosis of HenochSchonlein Nephritis in Children
OBJECTIVE: To analyze the relationship between the clinical and pathological effects and longterm prognosis in children with Henoch Schonlein nephritis. METHODS: Changes of clinical pathology were studied in 32 children with Henoch Schonlein nephritis and 19 cases of them were followed over an 8 to 14 year period. RESULTS: Acute nephritis ranked first (50%) and the nephritic syndrome ranked second (40%) in the clinical classification of Henoch Schonlein nephritis; the majority had pathological changes of Grade Ⅱ~Ⅲ. The rate of recovery of acute nephritis and the nephritic syndrome was 55.6% and 28.6%, respectively. The rate of recovery and deterioration of Grade Ⅰ~Ⅲ pathological changes was 43.8% and 12.5%, respectively. Of the patients with Grade Ⅳ~Ⅴ pathological changes, 66.7% deteriorated or died. CONCLUSIONS: The prognosis of acute nephritis was better than that of the nephritic syndrome, and longterm prognosis is closely associated with the clinical classification and pathology
Henoch Schonlein nephritis / Clinical / Pathological / Long term prognosis / Child