OBJECTIVE: To explore the possibility of making an early diagnosis on Kawasaki disease (KD). METHODS: Medical records of 69 children with KD were reviewed retrospectively. Diagnosis of KD was based on current diagnostic criteria of KD. RESULTS: In the 69 cases of KD the incidence of fever, lips injection and/or cheilosis, skin rashes, and bilateral nonexudative conjunctival injection were 100%, 92%, 84% and 81% respetfively within 5 days since onset. The incidence of the perianal skin redness and/or desquamation appeared in 8 days after onset and BCG inoculation scar reaction——“BCG scar” reaction appeared earlier (in 3 days after onset). CONCLUSIONS: When a child developed the Kawasaki appearance—fever, bilateral nonexudative conjunctival injection and lips injection and/or cheilosis in the early stage of febrile illness, KD should be highly suspected. “BCG scar reaction” and the perianal skin redness, even desquamation may be helpful to make an early diagnosis of KD.