Risk factors and pathogens of nosocomial infection in preterm infants

WANG Yu-Hong; XIA Shi-Wen

PDF(997 KB)

Chinese Journal of Contemporary Pediatrics ›› 2009, Vol. 11 ›› Issue (12) : 980-982.

CLINICAL RESEARCH

Risk factors and pathogens of nosocomial infection in preterm infants

WANG Yu-Hong, XIA Shi-Wen

Author information +

History +

Abstract

OBJECTIVE: To investigate the risk factors and the pathogens of nosocomial infection in preterm infants. METHODS: The medical data of 197 preterm infants with nosocomial infection were retrospectively studied. RESULTS: The incidence of nosocomial infection was 22.2% (197/887). Small gestational age (OR=4.125, P<0.05), low birth weight (OR=5.450, P<0.05), mechanical ventilation therapy (OR=4.435, P<0.05) and delayed enteral feedings (OR=3.765, P<0.05) were found to be important risk factors for nosocomial infection. Klebsiella was the main pathogen (22.3%), followed by Staphylococcus (18.4%). CONCLUSIONS: Hygienic handwashing, decreasing invassive procedures and an early start of enteral feeding are crucial for preventing nosocomal infection in preterm infants. Klebsiella is the main pathogen of nosocomal infections［Chin J Contemp Pediatr, 2009, 11 (12):980-982］

Key words

Nosocomial infection / Risk factor / Preterm infant

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

WANG Yu-Hong, XIA Shi-Wen. Risk factors and pathogens of nosocomial infection in preterm infants[J]. Chinese Journal of Contemporary Pediatrics. 2009, 11(12): 980-982

References

［1］Carey AJ, Saiman L, Polin RA. Hospital-acquired infections in the NICU: epidemiology for the new millennium［J］. Clin Perinatol, 2008, 35(1):223-49.
［2］Newby J. Nosocomial infection in neonates: inevitable or preventable?［J］. J Perinat Neonatal Nurs, 2008, 22(3):221-227.
［3］杨琳琳, 陈运斌. 丙种球蛋白治疗早产儿呼吸机相关性肺炎疗效观察［J］.中国妇幼保健, 2003, 18（9）:50-51.
［4］Horii KA, Nopper AJ. Emerging cutaneous infections in the premature neonate［J］. Adv Dermatol, 2007, 23:177-195.
［5］Benjamin DK Jr, Stoll BJ, Fanaroff AA, McDonald SA, Oh W, Higgins RD, et al. Neonatal candidiasis among extremely low birth weight infants: risk factors, motality rates, and neurodevelopmental outcome at 18 to 22 months［J］. Pediatrics, 2006, 117(1):84-92.
［6］丁艳,沈月华,施婴婴.新生儿重症监护室肺炎克雷伯菌败血症危险因素及临床特征［J］.中国新生儿科杂志, 2008, 23(6):334-335.
［7］Soltau TD, Schelonka RL. Immune modification to prevent nosocomial sepsis in hospitalized newborns［J］. NeoRreviews, 2008, 9（5）:199-205.
［8］Lemus-Varela Mde L, Alberto VS, Arriaga-Dávila Jde J. Clinical and laboratory parameters in neonatal nosocomial sepsis［J］. Gac Med Mex, 2008, 144(5):409-411.