Association of human parvovirus B19 infection and childhood idiopathic thrombocytopenic purpura: a meta analysis of Chinese literatures

ZHANG Yao-Dong; HU Qun; LIU Shuang-You; LIU Ai-Guo; WANG Guan-Ling; XIONG Hao; SUN Yan

PDF(1198 KB)

Chinese Journal of Contemporary Pediatrics ›› 2009, Vol. 11 ›› Issue (12) : 999-1001.

Association of human parvovirus B19 infection and childhood idiopathic thrombocytopenic purpura: a meta analysis of Chinese literatures

ZHANG Yao-Dong, HU Qun, LIU Shuang-You, LIU Ai-Guo, WANG Guan-Ling, XIONG Hao, SUN Yan

Author information +

History +

Abstract

OBJECTIVE: To study the relationship between human parvovirus B19 infection and childhood idiopathic thrombocytopenic purpura (ITP) by the principle of evidence based medicine. METHODS: Papers related to the relationship between human parvovirus B19 infection and childhood ITP published between 1994 and 2008 were retrieved electronically from the Chinese Journals Full-text Database and the Wanfang Data. These relevant papers on case-control trials were statistically studied by meta analysis. RESULTS: Eight papers that met the inclusion criteria were included for this meta analysis. Five hundred and sixteen cases of childhood ITP and 246 healthy controls were enrolled. The meta analysis showed that the incidence of human parvovirus B19 infection in the ITP group was significantly higher than that in the control group (OR=13.71, 95% CI=7.07-26.59, Z=7.75, P<0.01). CONCLUSIONS: Human parvovirus B19 infection is closely associated with childhood ITP.［Chin J Contemp Pediatr, 2009, 11 (12):999-1001］

Key words

Human parvovirus B19 / Idiopathic Thrombocytopenic Purpura / Meta analysis / Child

Cite this article

EndNote

Ris (Procite)

Bibtex

Download Citations

ZHANG Yao-Dong, HU Qun, LIU Shuang-You, LIU Ai-Guo, WANG Guan-Ling, XIONG Hao, SUN Yan. Association of human parvovirus B19 infection and childhood idiopathic thrombocytopenic purpura: a meta analysis of Chinese literatures[J]. Chinese Journal of Contemporary Pediatrics. 2009, 11(12): 999-1001

References

［1］Hida M, Shimamura Y, Ueno E, Watanabe J. Childhood idiopathic thrombocytopenic purpura associated with human parvovirus B19 infection［J］. Pediatr Int, 2000, 42(6):708-710.
［2］Kerr JR. Pathogenesis of human parvovirus B19 in rheumatic disease［J］. Ann Rheum Dis, 2000, 59(9):672-683.
［3］中华医学会儿科学分会血液学组. 特发性血小板减少性紫癜诊疗建议［J］.中华儿科杂志, 1998, 37（1）：50-51.
［4］毕春霞，闫志勇，王斌．病毒感染与儿童特发性血小板减少性紫癜的关系［J］．青岛大学医学院学报, 2003, 29（1）：45-46.
［5］季正华,黄益萍．探讨病毒感染与儿童特发性血小板减少性紫癜的关系［J］．放射免疫学杂志，2004 ，17（5 ）：411-413.
［6］李爱敏，张继红，孙洪亮，王颖华．人类细小病毒B19感染与小儿急性特发性血小板减少性紫癜［J］．小儿急救医学, 2003, 10（5）：295-296.
［7］刘艳奎,金京春,马天泽,金春海．急性特发性血小板减少性紫癜与人细小病毒B19 感染的关系［J］．延边大学医学学报，2006， 29 （4 ）：266-267.
［8］祁怀山，鲁智勇，杨丽萍，庄寅, 郭一峰,姚志荣．儿童特发性血小板减少性紫癜与细小病毒B19感染关系探讨［J］．临床儿科杂志，2006， 24 （7）：582-584.
［9］束晓梅,冒青,李娟．人细小病毒B19 感染与儿童急性特发性血小板减少性紫癜发病关系的探讨［J］．中国实用儿科杂志，2003 ，18 （4）：230-231.
［10］宪莹,徐酉华,于洁．人细小病毒B19 感染与小儿特发性血小板减少性紫癜［J］．重庆医学，2005，34 （9 ）：1289-1290.
［11］张艳，郭慧颖，彭韶．特发性血小板减少性紫癜患儿血清微小病毒检测［J］．郑州大学学报(医学版)，2004，9（6）：1059-1061.
［12］曾佑群, 刘瑜, 张振琪．人细小病毒B19感染与儿童血液疾病的关系［J］．实用医技杂志，2003，10（6）：569-570.
［13］张宝荣，王琦，贾万英，李静岩,杨洪江．伴细小病毒B19感染的小儿特发性血小板减少性紫癜治疗的临床研究［J］．中华血液学杂志，1999，20（9）：480-480.
［14］许东亮，张国成，张笑飞，钱新宏．小儿血液系统疾病人细小病毒B19感染的研究［J］．中国当代儿科杂志, 2002, 4(3):221-222.
［15］严媚，古丽娜·沙丁, 顾立达．人类微小病毒B19 与小儿血液病的关系［J］．新疆医科大学学报, 2003, 26 (5)：476-477.
［16］陈斯一, 沈晓娜, 陈慧．人微小病毒B19 感染与小儿血液系统疾病的相关性初步研究［J］．海峡预防医学杂志, 2005, 11（4）：81-82.
［17］宪莹, 徐酉华．小儿特发性血小板减少性紫癜与病毒感染的关系［J］．重庆医科大学学报，2004，29（3）：375-376.