Investigation of allergens in 3 504 children with allergic diseases

SHU Ye; TANG Jian-Ping; ZHANG Dan; ZENG Ying-Hong; ZHOU Bin

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Chinese Journal of Contemporary Pediatrics ›› 2010, Vol. 12 ›› Issue (09) : 720-722.

CLINICAL RESEARCH

Investigation of allergens in 3 504 children with allergic diseases

SHU Ye, TANG Jian-Ping, ZHANG Dan, ZENG Ying-Hong, ZHOU Bin

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Abstract

OBJECTIVE: To investigate the allergens of various allergic diseases in children. METHODS: Serum levels of Fx5E, Phadiatop and specific IgE were measured by the UniCAP100 System in 3 504 children with allergic diseases. RESULTS: The positive rate of aeroallergens was obviously higher than that of food allergens in children with allergic rhinitis, allergic conjunctivitis, asthma and papular urticaria. In contrast, the positive rate of food allergens was obviously higher than that of aeroallergens in children with Henoch-Schonlein purpura and digestive diseases. The serum specific IgE level of aeroallergens was higher than that of food allergens. The dust and mite specific IgE levels reached to grade 6, while the food allergen specific IgE levels were lower than grade 3. CONCLUSIONS: Aaeroallergens or food allergens vary remarkably in different allergic diseases in children. The level of specific IgE of aeroallergens is higher than that of food allergens.［Chin J Contemp Pediatr, 2010, 12 (9):720-722］

Key words

Allergic disease / Allergen / Specific IgE / Child

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SHU Ye, TANG Jian-Ping, ZHANG Dan, ZENG Ying-Hong, ZHOU Bin. Investigation of allergens in 3 504 children with allergic diseases[J]. Chinese Journal of Contemporary Pediatrics. 2010, 12(09): 720-722

References

［1］Dolen WK. IgE antibody in the serum-detection and diagnostic significance［J］.Allergy, 2003, 58(8):717-723.
［2］Yunginger JW, Ahlstedt S, Eggleston PA, Homburger HA, Nelson HS, Ownby DR, et al. Quantitative IgE antibody assays in allergic diseases［J］. J Allergy Clin Immunol, 2000,105(6 Pt 1):1007-1084.
［3］Sly RM. Changing prevalence of allergic rhinitis and asthma［J］.Ann Allergy Asthma Immunol, 1999, 82(3):233-248.
［4］Crane J, Wickens K, Beasley R, Fitzharris P. Asthma and allergy: a worldwide problem of meanings and management?［J］. Allergy, 2002, 57(8):663-672.
［5］戴劲盛，李卫国，李佳，顾晓鸣. 呼吸道变态反应性疾病患儿植物类变应原反应性研究［J］.临床儿科杂志, 2009, 27（5）：455-457.
［6］虞伟，陈斐，罗冰，刘国瑞，黄梅，李晓军，等.南京地区过敏性疾病患者特异性变应原检测结果报告［J］.中国实验诊断学, 2009， 13（6）：784-786.
［7］王玥，张璇，王超，李孟荣，李昌崇，李迎春. 908例哮喘儿童皮肤点刺实验分析［J］. 中国当代儿科杂志, 2009， 11（7）：559-561.
［8］吴宁,汤小晖,李雯，陈英.武汉市尘螨致敏的调查［J］.中国医师杂志, 2004, 6(7):1004-1005.
［9］Sharma HP, Hansel NN, Matsui E, Diette GB, Eggleston P, Breysse P. Indoor environmental influences on children′s asthma［J］. Pediatr Clin North Am, 2007, 54(1):103-120.