LI Ping,TONG Yu,MAO Meng. Relationship between telomere/telomerase and the developmental origins of metabolic syndrome[J]. 中国当代儿科杂志, 2010, 12(12): 1008-1012.
LI Ping,TONG Yu,MAO Meng. Relationship between telomere/telomerase and the developmental origins of metabolic syndrome[J]. CJCP, 2010, 12(12): 1008-1012.
［1］Bruce KD, Byrne CD. The metabolic syndrome: common origins of a multifactorial disorder［J］. Postgrad Med J, 2009, 85(1009): 614-621.
［2］Saretzki G. Telomerase, mitochondria and oxidative stress［J］. Exp Gerontol, 2009, 44(8): 485-492.
［3］Petter DG, Mark AH. The developmental origins of health and disease［M］// Marelyn WE, Julie O. Early Life Origins of Health and Disease, Vol 573. US: Springer US, 2007: 1-7.
［4］Harman D. The biologic clock: the mitochondria?［J］. J Am Geriatr Soc, 1972, 20(4): 145-147.
［6］Haendeler J, Drse S, Büchner N, Jakob S, Altschmied J, Goy C, et al. Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage［J］. Arterioscler Thromb Vasc Biol, 2009, 29(6): 929-935.
［7］Ahmed S, Passos JF, Birket MJ, Beckmann T, Brings S, Peters H, et al. Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress［J］. J Cell Sci, 2008, 121(Pt 7): 1046-1053.
［8］Kovalenko OA, Caron MJ, Ulema P, Medrano C, Thomas AP, Kimura M, et al. A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction［J］. Aging Cell, 2010, 9(2): 203-219.
［9］Massard C, Zermati Y, Pauleau AL, Larochette N, Métivier D, Sabatier L, et al. hTERT: a novel endogeneous inhibitor of the mitochondrial cell death pathway［J］. Oncogene, 2006, 25(33): 4505-4514.
［10］Bagheri S, Nosrati M, Li S, Fong S, Torabian S, Rangel J, et al. Genes and pathways downstream of telomerase in melanoma metastasis［J］. Proc Natl Acad Sci USA, 2006, 103(30): 11306-11311.
［13］Oeseburg H, de Boer RA, van Gilst WH, van der Harst P. Telomere biology in healthy aging and disease［J］. Pflugers Arch, 2010, 459(2): 259-268.
［14］Salpea KD, Humphries SE. Telomere length in atherosclerosis and diabetes［J］. Atherosclerosis, 2010, 209(1): 35-38.
［15］Benetos A, Okuda K, Lajemi M, Kimura M, Thomas F, Skurnick J, et al. Telomere length as an indicator of biological aging: the gender effect and relation with pulse pressure and pulse wave velocity［J］. Hypertension, 2001, 37(2): 381-385.
［16］Das B, Pawar N, Saini D, Seshadri M. Genetic association study of selected candidate genes (ApoB, LPL, Leptin) and telomere length in obese and hypertensive individuals［J］. BMC Med Genet, 2009, 10: 99.
［17］Yang ZW, Huang X, Jiang H, Zhang YR, Liu HX, Qin C, et al. Short telomeres and prognosis of hypertension in a Chinese population［J］. Hypertension, 2009, 53(4): 639-645.
［18］Brouilette SW, Whittaker A, Stevens SE, van der Harst P, Goodall AH, Samani NJ. Telomere length is shorter in healthy offspring of subjects with coronary artery disease:support for the telomere hypothesis［J］. Heart, 2008, 94(4): 422-425.
［19］Hamet P, Thorin-Trescases N, Moreau P, Dumas P, Tea BS, deBlois D, et al. Workshop: excess growth and apoptosis: is hypertension a case of accelerated aging of cardiovascular cells?［J］. Hypertension, 2001, 37(2 Part 2): 760-766.
［20］Cao Y, Li H, Mu FT, Ebisui O, Funder JW, Liu JP. Telomerase activation causes vascular smooth muscle cell proliferation in genetic hypertension［J］. FASEB J, 2002, 16(1): 96-98.
［21］Sampson MJ, Winterbone MS, Hughes JC, Dozio N, Hughes DA. Monocyte telomere shortening and oxidative DNA damage in type 2 diabetes［J］. Diabetes Care, 2006, 29(2): 283-289.
［22］Kim SM, Parks CG, DeRoo LA, Chen H, Taylor JA, Cawthon RM, et al. Obesity and weight gain in adulthood and telomere length［J］. Cancer Epidemiol Biomarkers Prev, 2009, 18(3): 816-820.
［23］Epel ES, Lin J, Wilhelm FH, Wolkowitz OM, Cawthon R, Adler NE, et al. Cell aging in relation to stress arousal and cardiovascular disease risk factors［J］. Psychoneuroendocrinology, 2006, 31(3): 277-287.
［24］Nordfj-ll K, Eliasson M, Stegmayr B, Melander O, Nilsson P, Roos G. Telomere length is associated with obesity parameters but with a gender difference［J］. Obesity (silver spring), 2008, 16(12): 2682-2689.
［25］O′Donnell CJ, Demissie S, Kimura M, Levy D, Gardner JP, White C, et al. Leukocyte telomere length and carotid artery intimalmedial thickness: the Framingham Heart Study［J］. Arterioscler Thromb Vasc Biol, 2008, 28(6): 1165-1171.
［26］Zannolli R, Mohn A, Buoni S, Pietrobelli A, Messina M, Chiarelli F, et al. Telomere length and obesity［J］. Acta Paediatr, 2008, 97(7): 952-954.
［27］Cherkas LF, Hunkin JL, Kato BS, Brent Richards J, Gardner JP, Surdulescu GL, et al. The association between physical activity in leisure time and leukocyte telomere length［J］. Arch Intern Med, 2008, 168(2): 154-158.
［28］Richards JB, Valdes AM, Gardner JP, Paximadas D, Kimura M, Nessa A, et al. Higher serum vitamin D concentrations are associated with longer leukocyte telomere length in women［J］. Am J Clin Nutr, 2007, 86(5): 1420-1425.
［29］Nordfj-ll K, Eliasson M, Stegmayr B, Lundin S, Roos G, Nilsson PM. Increased abdominal obesity, adverse psychosocial factors and shorter telomere length in subjects reporting early ageing; the MONICA Northern Sweden Study［J］. Scand J Public Health, 2008, 36(7): 744-752.
［30］Okuad K, Bardeguez A, Gardner JP, Rodriguez P, Ganesh V, Kimura M, et al. Telomere length in the newborn［J］. Pediatr Res, 2002, 52(3): 377-381.
［31］Kudo T, Izutsu T, Sato T. Telomerase activity and apoptosis as indicators of ageing in placenta with and without intrauterine growth retardation［J］. Placenta, 2000, 21(5-6): 493-500.
［32］Izutsu T, Kudo T, Sato T, Nishiya I, Ohyashiki K, Mori M, et al. Telomerase activity in human chorionic villi and placenta determined by TRAP and in situ TRAP assay［J］. Placenta, 1998, 19(8): 613-618.
［33］Davy P, Nagata M, Bullard P, Fogelson NS, Allsopp R. Fetal growth restriction is associated with accelerated telomere shortening and increased expression of cell senescence markers in the placenta［J］. Placenta, 2009, 30(6): 539-542.
［34］Friedrich U, Schwab M, Griese EU, Fritz P, Klotz U. Telomeres in neonates: new insights in fetal hematopoiesis［J］. Pediatr Res, 2001, 49(2): 252-256.
［35］Akkad A, Hastings R, Konje JC, Bell SC, Thurston H, Williams B. Telomere length in small-for-gestational-age babies［J］. BJOG, 2006, 113(3): 318-323.
［36］Curhan GC, Chertow GM, Willett WC, Spiegelman D, Colditz GA, Manson JE, et al. Birth weight and adult hypertension and obesity in women［J］. Circulation, 1996, 94(6): 1310-1315.
［37］Parsons TJ, Power C, Manor O. Fetal and early life growth and body mass index from birth to early adulthood in 1958 British cohort: longitudinal study［J］. BMJ, 2001, 323(7325): 1331-1335.
［38］Nobili V, Alisi A, Panera N, Agostoni C. Low birth weight and catch-up-growth associated with metabolic syndrome: a ten year systematic review［J］. Pediatr Endocrinol Rev, 2008, 6(2): 241-247.
［39］Fernandes G, Friend P, Yunis EJ, Good RA. Influence of dietary restriction on immunologic function and renal disease in (NZB × NZW) F1 mice［J］. Proc Natl Acad Sci U S A, 1978, 75(3): 1500-1504.
［40］Masoro EJ, Iwasaki K, Gleiser CA, McMahan CA, Seo EJ, Yu BP. Dietary modulation of the progression of nephropathy in aging rats: an evaluation of the importance of protein［J］. Am J Clin Nutr, 1989, 49(6): 1217-1227.
［41］Yu BP, Masoro EJ, Murata I, Bertrand HA, Lynd FT. Life span study of SPF Fischer 344 male rats fed ad libitum or restricted diets: longevity, growth, lean body mass and disease［J］. J Gerontol, 1982, 37(2): 130-141.
［42］Demerath EW, Cameron N, Gillman MW, Towne B, Siervogel RM. Telomeres and telomerase in the fetal origins of cardiovascular disease: a review［J］. Hum Biol, 2004, 76(1): 127-146.
［43］Jennings BJ, Ozanne SE, Dorling MW, Hales CN. Early growth determines longevity in male rats and may be related to telomere shortening in the kidney［J］. FEBS Lett, 1999, 448(1): 4-8.
［44］Tarry-Adkins JL, Chen JH, Smith NS, Jones RH, Cherif H, Ozanne SE. Poor maternal nutrition followed by accelerated postnatal growth leads to telomere shortening and increased markers of cell senescence in rat islets［J］. FASEB J, 2009, 23(5): 1521-1528.
［46］Luyckx VA, Compston CA, Simmen T, Mueller TF. Accelerated senescence in kidneys of low-birth-weight rats after catch-up growth［J］. Am J Physiol Regul Integr Comp Physiol, 2009, 297(6): F1697-F1705.
［48］Richards JB, Valdes AM, Gardner JP, Kato BS, Siva A, Kimura M, et al. Homocysteine levels and leukocyte telomere length［J］. Atherosclerosis, 2008, 200(2): 271-277.
［49］Paul L, Cattaneo M, D′Angelo A, Sampietro F, Fermo I, Razzari C, et al.Telomere length in peripheral blood mononuclear cells is associated with folate status in men［J］. J Nutr, 2009, 139(7): 1273-1278.
［50］Atkinson SP, Keith WN. Epigenetic control of cellular senescence in disease: opportunities for therapeutic intervention［J］. Expert Rev Mol Med, 2007,9(7):1-26.
［51］Atkinson SP, Hoare SF, Glasspool RM, Nicol Keith W. Lack of telomerase gene expression in alternative lengthening of telomere cells is associated with chromatin remodeling of the hTR and hTERT gene promoters［J］. Cancer Res, 2005, 65(17): 7585-7590.
［52］Ross SA, Milner JA. Epigenetic modulation and cancer: effect of metabolic syndrome?［J］. Am J Clin Nutr, 2007, 86(3): 872-877.
［53］Joss-Moore LA, Metcalfe DB, Albertine KH, McKnight RA, Lane RH. Epigenetics and fetal adaptation to perinatal events: diversity through fidelity［J］. J Anim Sci, 2010, 88(13 Suppl): E216-E222.
［54］Mathers JC, McKay JA. Epigenetics-potential contribution to fetal programming［J］. Adv Exp Med Biol, 2009, 646: 119-123.
