OBJECTIVE: To study the prevalence and clinical features of febrile convulsion (FC) among pupils in the Wenzhou region, Zhejiang Province, China. METHODS: Using a random stratified cluster sampling method, 6406 children under 12 years from two primary schools of urban areas and two primary schools of rural areas were surveyed. RESULTS: The prevalence of FC was 3.67% (235/6406). Most children (75.7%) experienced their first onset of FC at 6 months to 3 years of age (median: 16 months). The seizures were generalized (95.3%, 224/235), with a duration of less than 10 min utes (86.4%, 203/235). FC was developed into epilepsy in 13 children (5.5%) who all sufferred from complex FC. Relapses were noted in 88 cases (37.4%), among whom 38 patients had only 1 recurrence and 50 patients had 2 or more relapses. EEG was performed in 200 cases, among whom 12(6.0%) showed abnormalities. CONCLUSIONS: The prevalence of FC is 3.67% among pupils in the Wenzhou region. The seizures are generalized, with a short duration. A part of complex FC can be developed into subsequent epilepsy.
Key words
Febrile convulsion /
Epidemiology /
Child
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References
［1］吴家骅.热性惊厥［M］//吴希如，林庆.小儿神经系统疾病基础与临床.第2版.北京:人民卫生出版社, 2009: 576-589.
［2］Shimony A, Afawi Z, Asher T, Mahajnah M, Shorer Z. Epidemiological characteristics of febrile seizures-comparing between Bedouin and Jews in the Southern part of Israel［J］. Seizure, 2009, 18 (1): 26-29.
［3］李雪瑞.68例小儿热性惊厥复发与转为癫癎危险因素临床分析［J］.中国厂矿医学，2007，20（1）：45-46.
［4］郭虎, 郑帼.热性惊厥处理指南解读［J］.实用儿科临床杂志，2011,26（6）：467-468.
［5］赵环，肖成华，徐建洋.热性惊厥的研究进展［J］.医学信息，2011，24（5）：2853-2855.
［6］Duffner PK, Berman PH, Baumann RJ, Fisher PG, Green JL, Schneider S, et al. Neurodiagnostic evaluation of the child with a simple febrile seizure［J］. Pediatrics, 2011, 127(2): 389-394.
［7］Hirabayashi Y, Okumura A, Kondo T, Magota M, Kawabe S, Kando N, et al. Efficacy of a diazepam suppository at preventing febrile seizure recurrence during a single febrile illness［J］. Brain Dev, 2009, 31(6): 414-418.
［8］Pavlidou E, Tzitiridou M, Kontopoulos E, Panteliadis CP. Which factors determine febrile seizure recurrence? A prospective study［J］. Brain Dev, 2008, 30(1): 7-13.
［9］Kolahi AA, Tahmooreszadeh S. First febrile convulsions: inquiry about the knowledge, attitudes and concerns of the patients' mothers［J］. Eur J Pediatr, 2009, 168(2): 167-171.
［10］邱鹏玲，施亿赟，孙道开，王艺.口服抗癫癎药物治疗儿童热性惊厥的临床与脑电图分析［J］. 中国当代儿科杂志，2011，13 (2)：123-126.
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