Autism spectrum disorder-like symptoms in the population with intellectual disability aged 6 to 18 years

ZHOU Hao; LI Chun-Pei; WANG Tian-Qi; LONG Sha-Sha; DU Xiao-Nan; MA Yu; WANG Yi

doi:10.7499/j.issn.1008-8830.2019.05.009

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Chinese Journal of Contemporary Pediatrics ›› 2019, Vol. 21 ›› Issue (5) : 445-449. DOI: 10.7499/j.issn.1008-8830.2019.05.009

CLINICAL RESEARCH

Autism spectrum disorder-like symptoms in the population with intellectual disability aged 6 to 18 years

ZHOU Hao^1,2, LI Chun-Pei¹, WANG Tian-Qi¹, LONG Sha-Sha¹, DU Xiao-Nan¹, MA Yu¹, WANG Yi¹

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Abstract

Objective To investigate the incidence of autism spectrum disorder (ASD)-like symptoms in the population with intellectual disability (ID). Methods The students with ASD or ID, aged 6-18 years, who studied in a special school in Shanghai from January to June, 2017, as well as the typically developing (TD) population of the same age, who studied in a general school in Shanghai during the same period, were enrolled. Social Responsiveness Scale (SRS) was completed by their parents or other guardians, and the ASD-like symptoms were evaluated. Results A total of 69 subjects with ASD, 74 subjects with ID and 177 TD subjects were enrolled. The ID group had a significantly higher SRS-positive rate than the TD group (47.3% vs 1.7%; P < 0.001) and a significantly lower SRS-positive rate than the ASD group (47.3% vs 87.0%; P < 0.001). The total score of SRS was 114±26 in the ASD group, 80±24 in the ID group and 38±19 in the TD group. The ID group had a significantly higher total score of SRS than the TD group (P < 0.05), and the score on the subscale of social cognition showed the most significant difference between the two groups (Cohen's d=2.00). There were no significant differences in the total score of SRS and the scores on each subscale of SRS between the mild-to-moderate ID and severe-to-extremely severe ID groups (P > 0.05), and there was no significant correlation between SRS score and IQ (P > 0.05). Conclusions The ID population aged 6-18 years has more ASD-like symptoms than the general population, and ASD screening and intervention should be performed for the ID population as early as possible.

Key words

Intellectual disability / Autism spectrum disorder-like symptom / Social Responsiveness Scale / Child

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ZHOU Hao, LI Chun-Pei, WANG Tian-Qi, LONG Sha-Sha, DU Xiao-Nan, MA Yu, WANG Yi. Autism spectrum disorder-like symptoms in the population with intellectual disability aged 6 to 18 years[J]. Chinese Journal of Contemporary Pediatrics. 2019, 21(5): 445-449 https://doi.org/10.7499/j.issn.1008-8830.2019.05.009

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