Shift of apoptosis in lymphocyte in children with myocarditis
WANG Wen-Ti, JIANG Yu-Hong, ZHOU Dong, LI Xiu-Zhen, SUN Yu-Ping, MA Shao-Chun
Qingdao Children's Hospital, Qingdao 266011
Abstract Objective To understand the shift of apoptosis in lymphocyte of children with myocarditis, to investigate the pathogenesis of myocarditis.Methods To detect the shift of apoptosis in T-lymphocyte by immunofluorescence among 41 children with myocarditis including infection of virus and mycoplasma, and the alteration of T-lymphocytic subgroup and immunoglobulin at the same time. Results The apoptosis of lymphocytes in myocarditis group was higher than that of normal group, and T-lymphocytic subgroup CD 4 +, CD 4 +/CD 8 + were distinctly descented, CD 8 + was elevated(P<0.01). Conclusions The excessive apoptosis of lymphocytes lead imbalance of the amount. The low functions of T-lymphocyte and humour immunity are one of the important cause of the myocarditis induced by the infection of virus or mycoplasma.
Key words ：
Lymphocyte
Myocarditis
Apoptosis
Cite this article:
WANG Wen-Ti,JIANG Yu-Hong,ZHOU Dong et al. Shift of apoptosis in lymphocyte in children with myocarditis[J]. 中国当代儿科杂志, 1999, 1(1): 7-8.
WANG Wen-Ti,JIANG Yu-Hong,ZHOU Dong et al. Shift of apoptosis in lymphocyte in children with myocarditis[J]. CJCP, 1999, 1(1): 7-8.
URL:
http://www.zgddek.com/EN/ OR http://www.zgddek.com/EN/Y1999/V1/I1/7
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