Abstract OBJECTIVE: To investigate the main inhalant allergens and their distribution patterns in children with allergic diseases from Xi’an and the surrounding area and to provide evidence for the prevention and treatment of allergic diseases in children. METHODS: Skin prick test was performed using liquid with 13 standardized allergens (ALK-ABELL, Denmark) on 3085 children from Xi′an and the surrounding area who were treated for allergic diseases between July 2006 and July 2011, to detect inhalant allergens. RESULTS: Of the 3085 patients, 1368 (44.34%) had positive SPT results, with the most prevalent inhalant allergen being Dermatophagoides pteronyssinus (804 cases, 26.06%), followed by Dermatophagoides farinae (793 cases, 25.71%), Blomia tropicalis (440 cases, 14.26%), mugwort (282 cases, 9.14%), and cat hair (204 cases, 6.61%). The positive rates were 28.66% in the <4 years group, 41.85% in the 4-6 years group, and 58.61% in the 7-15 years group (P<0.01). Males had a significantly higher SPT positive rate than females (47.78% vs 38.50%； P<0.05). The SPT positive rate was highest in children with allergic rhinitis (72.41%), followed by bronchial asthma (62-25%), allergic dermatosis (45.83%), and allergic purpura (36.28%). CONCLUSIONS: In children from Xi′an and the surrounding area, the main inhalant allergens for allergic diseases include Dermatophagoides pteronyssinus, Dermatophagoides farinae, Blomia tropicalis, mugwort and cat hair. The SPT positive rate increases with age. Male children have a higher SPT positive rate than female children. The SPT positive rate is highest in children with allergic rhinitis.
CHENG Sheng-Quan,QIANG Huan,DING Cui-Ling et al. Clinical significance of skin prick test for inhalant allergens in 3085 children with allergic diseases[J]. 中国当代儿科杂志, 2012, 14(10): 751-754.
CHENG Sheng-Quan,QIANG Huan,DING Cui-Ling et al. Clinical significance of skin prick test for inhalant allergens in 3085 children with allergic diseases[J]. CJCP, 2012, 14(10): 751-754.
［1］Chan EY,Dundas I,Bridge PD,Healy MJ,McKenzie SA.Skin-prick testing as a diagnostic aid for childhood asthma［J］.Pediatr Pulmonol, 2005, 39(6): 558-562.
［2］Niel-Weise BS, Snoeren RL, van den Broek PJ.Policies for endotracheal suctioning of patients receiving mechanical ventilation: a systematic review of randomized controlled trials［J］.Infect Control Hosp Epidemiol, 2007, 28(5): 531-536.
［10］Miraglia Del, Giudice M, Pedulltt M, Piacentini GL, Capristo C, Brunese FP, Decimo F, et al. Atopy and house dust mite sensitization as risk factors for asthma in children［J］.Alergy, 2002, 57(2): 169-172.
［11］Osman M, Hansell AL, Simpson CR, Hollowell J, Helms PJ. Gender-specific presentations for asthma, allergic rhinitis and eczema in primary care［J］. Prim Care Respir J, 2007, 16(1): 28-35.
