朗格汉斯组织细胞增生症儿童肝脏受累的CT表现

doi:10.7499/j.issn.1008-8830.2013.02.012

Abstract
Figure/Table
References(12)
Related Citation (15)
Read Tracking
Download Tracking

Download: PDF (1290 KB)
Export: BibTeX | EndNote (RIS) Supporting Info

Abstract OBJECTIVE: To investigate the computed tomography (CT) manifestations of liver involvement in children with Langerhans cell histiocytosis (LCH). METHODS: Retrospective analysis was performed on 9 LCH children with liver involvement confirmed by clinical, laboratory and pathological examinations to investigate the CT manifestations of this condition. These children, including 6 males and 3 females, had undergone both plain CT scan and dual-phase (the arterial and portal venous phases) contrast-enhanced CT scan. RESULTS: The main CT manifestations included hepatomegaly (8 cases); periportal dendritic hypodense lesions or “periportal halo sign” (7 cases) which were mildly or moderately enhanced in the arterial phase; intrahepatic bile duct dilatation (5 cases); lymphadenopathy in the hepatic hilar or retroperitoneal region (4 cases); and diffuse small hypodense nodules (3 cases), which showed annular enhancement on the contrastenhanced CT scan. CONCLUSIONS: CT findings may be helpful in the early diagnosis and treatment of LCH in children.

	Service

	E-mail this article
	Add to my bookshelf
	Add to citation manager
	E-mail Alert
	RSS
	Articles by authors
	LIU Hui
	LONG Xue-Ying
	LI Wen-Zheng
	WANG Xiao-Yi
	CAO Jue
	LIU Zhi-Jun

Key words： Langerhans cell histiocytosis Liver Tomography X-ray computer Child

Cite this article:

LIU Hui,LONG Xue-Ying,LI Wen-Zheng et al. CT manifestations of liver involvement in children with Langerhans cell histiocytosis[J]. CJCP, 2013, 15(2): 121-124.

URL:

http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2013.02.012 OR http://www.zgddek.com/EN/Y2013/V15/I2/121

	［1］Henter JI, Tondini C, Pritchard J.Histiocyte disorders［J］.Crit Rev Oncol Hematol, 2004, 50(2): 157-174.
	［2］Jaffe R. Liver involvement in the histiocytic disorders of childhood［J］. Pediatr Dev Pathol, 2004, 7(3): 214-225.
	［3］芮耀耀. 郎格罕细胞组织细胞增生症42例临床分析［J］.中国当代儿科杂志, 2000, 2(2): 99-100.
	［4］Wong A, Ortiz-Neira CL, Reslan WA, Sharon R, Pinto-Rojas A, Kaura D, et al. Liver involvement in Langerhans cell histiocytosis［J］. Pediatr Radiol, 2006, 36(10): 1105-1107.
	［5］李欣，贾万英，杨志勇.儿童朗格尔汉斯细胞组织细胞增生症的CT 表现(附13 例分析)［J］. 中华放射学杂志，2001，35（1）：67-69.
	［6］Writing Group of the Histiocyte Society. Histiocytosis syndromes in children［J］. Lancet, 1987, 1(8526): 208-209.
	［7］Braier J, Cioccca M, Latella A, de Davila MG, Drajer M, Imventarza O. Cholestasis, sclerosing cholan gitis, and liver transplantation in Langerhans cell Histiocytosis［J］. Med Pediatr Oncol, 2002, 38(3): 178-182.
	［8］Egeler RM, D′Angio GJ, Langerhans cell histiocytosis［J］.J Pediatr, 1995, 127(1): 1-11.
	［9］Kilborn TN, Teh J, Goodman TR. Paediatric manifestations of Langerhans cell histiocytosis: a review of the clinical and radiological findings［J］. Clin Radiol, 2003, 58(4): 269-278.
	［10］Schmidt S, Eich G, Hanquinet S, Tsch-ppeler H, Waibel P, Gudinchet F. Extraosseous involvement of Langerhans′ cell histiocytosis in children［J］.Pediatr Radiol, 2004, 34(4): 313-321.
	［11］Konig CW, Pfannenberg C, Trubenbach J, Remy C, B-hmer GM, Ruck P, et al. MR cholangiography in the diagnosis of sclerosing cholangitis in Langerhans′ cell histiocytosis［J］. Eur Radiol, 2001, 11（12）: 2516-2520.
	［12］Caruso S, Miraglia R, Maruzzelli L, Luca A, Gridelli B. Biliary wall calcification in Langerhans cell histiocytosis: report of two cases［J］.Pediatr Radiol, 2008, 38(7): 791-794.