Abstract Objective To investigate the correlation between serum procalcitonin (PCT) level and pediatric critical illness score (PCIS) and their prognostic values in children with sepsis. Methods Sixty-one children with sepsis in the pediatric intensive care unit were enrolled. According to PCIS, these patients were divided into non-critical (n=18), critical (n=20), and extremely critical groups (n=23). Within 24 hours after admission, serum levels of PCT, C-reactive protein (CRP), and lactic acid (LA) and routine blood counts were measured. These parameters were compared between the three groups. The Pearson correlation analysis was performed to determine the correlation of PCT with PCIS and other serological parameters. Based on clinical outcomes, these patients were divided into survival (n=39) and death groups (n=22). The PCT, PCIS, and other serological parameters were compared between the two groups. Results The serum levels of PCT and CRP in the non-critical group were significantly lower than those in critical group and extremely critical groups (PPPr=-0.63, Pr=0.73, P=0.003). Compared with the death group, the survival group had significantly higher serum levels of PCT and LA (PPConclusions There is a good correlation between serum PCT level and PCIS. For children with sepsis, the lower the PCIS, the higher the serum PCT level, resulting in a poorer prognosis. A combination of serum PCT and PCIS can be used as an early prognostic indicator in children with sepsis.
QI Ying-Zheng. Prognostic values of serum procalcitonin level and pediatric critical illness score in children with sepsis[J]. CJCP, 2014, 16(2): 190-193.
QI Ying-Zheng. Prognostic values of serum procalcitonin level and pediatric critical illness score in children with sepsis[J]. CJCP, 2014, 16(2): 190-193.
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