[1] Hsu AP, Sampaio EP, Khan J, et al. Mutations in GATA2 are associated with the autosomal dominant and sporadic monocytopenia and mycobacterial infection (MonoMAC) syndrome[J]. Blood, 2011, 118(10): 2653-2655.
[2] Vinh DC, Patel SY, Uzel G, et al. Autosomal dominant and sporadic monocytopenia with susceptibility to mycobacteria, fungi, papillomaviruses, and myelodysplasia[J]. Blood, 2010, 115(8): 1519-1529.
[3] Bigley V, Haniffa M, Doulatov S, et al. The human syndrome of dendritic cell, monocyte, B and NK lymphoid deficiency[J]. J Exp Med, 2011, 208(2): 227-234.
[4] Calvo KR, Vinh DC, Maric I, et al. Myelodysplasia in autosomal dominant and sporadic monocytopenia immunodeficiency syndrome: diagnostic features and clinical implications[J]. Haematologica, 2011, 96(8): 1221-1225.
[5] Randolph GJ, Jakubzick C, Qu C. Antigen presentation by monocytes and monocyte-derived cells[J]. Curr Opin Immunol, 2008, 20(1): 52-60.
[6] Villadangos JA. Hold on, the monocytes are coming![J]. Immunity, 2007, 26(4): 390-392.
[7] Ostergaard P, Simpson MA, Connell FC, et al. Mutations in GATA2 cause primary lymphedema associated with a predisposition to acute myeloid leukemia (Emberger syndrome)[J]. Nature Genet, 2011, 43(10): 929-931.
[8] Gumina RJ, Kirschbaum NE, Piotrowski K, et al. Characterization of the human platelet/endothelial cell adhesion molecule-1 promoter: identification of a GATA-2 binding element required for optimal transcriptional activity[J]. Blood, 1997, 89(4): 1260-1269.
[9] Kappel A, Schlaeger TM, Flamme I, et al. Role of SCL/Tal-1, GATA, and ets transcription factor binding sites for the regulation of flk-1 expression during murine vascular development[J]. Blood, 2000, 96(9): 3078-3085.
[10] Kazenwadel J, Secker GA, Liu YJ, et al. Loss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculature[J]. Blood, 2012, 119(5): 1283-1291.
[11] Merad M, Manz MG. Dendritic cell homeostasis[J]. Blood, 2009, 113(15): 3418-3427.
[12] Murphy J, Summer R, Wilson AA, et al. The prolonged life-span of alveolar macrophages[J]. Am J Resp Cell Mol Biol, 2008, 38(4): 380.
[13] Haniffa M, Ginhoux F, Wang XN, et al. Differential rates of replacement of human dermal dendritic cells and macrophages during hematopoietic stem cell transplantation[J]. J Exp Med, 2009, 206(2): 371-385.
[14] Mace EM, Hsu AP, Monaco-Shawver L, et al. Mutations in GATA2 cause human NK cell deficiency with specific loss of the CD56bright subset[J]. Blood, 2013, 121(14): 2669-2677.
[15] McKenna HJ, Stocking KL, Miller RE, et al. Mice lacking flt3 ligand have deficient hematopoiesis affecting hematopoietic progenitor cells, dendritic cells, and natural killer cells[J]. Blood, 2000, 95(11): 3489-3497.
[16] Ishida H, Imai K, Honma K, et al. GATA-2 anomaly and clinical phenotype of a sporadic case of lymphedema, dendritic cell, monocyte, B-and NK-cell (DCML) deficiency, and myelodysplasia[J]. Eur J Pediatr, 2012, 171(8): 1273-1276.
[17] Dickinson RE, Griffin H, Bigley V, et al. Exome sequencing identifies GATA-2 mutation as the cause of dendritic cell, monocyte, B and NK lymphoid deficiency[J]. Blood, 2011, 118(10): 2656-2658.
[18] Pedone PV, Omichinski JG, Nony P, et al. The N-terminal fingers of chicken GATA-2 and GATA–3 are independent sequence-specific DNA binding domains[J]. EMBO J, 1997, 16(10): 2874-2882.
[19] Rodrigues NP, Tipping AJ, Wang Z, et al. GATA-2 mediated regulation of normal hematopoietic stem/progenitor cell function, myelodysplasia and myeloid leukemia[J]. Int J Biochem Cell Biol, 2012, 44(3): 457-460.
[20] Tsai FY, Keller G, Kuo FC, et al. An early haematopoietic defect in mice lacking the transcription factor GATA-2[J]. Nature, 1994, 371(6494): 221-226.
[21] Tsai FY, Orkin SH. Transcription factor GATA-2 is required for proliferation/survival of early hematopoietic cells and mast cell formation, but not for erythroid and myeloid terminal differentiation[J]. Blood, 1997, 89(10): 3636-3643.
[22] Ikonomi P, Noguchi CT, Miller W, et al. Levels of GATA-1/GATA-2 transcription factors modulate expression of embryonic and fetal hemoglobins[J]. Gene, 2000, 261(2): 277-287.
[23] Persons DA, Allay JA, Allay ER, et al. Enforced expression of the GATA-2 transcription factor blocks normal hematopoiesis[J]. Blood, 1999, 93(2): 488-499.
[24] Rodrigues NP, Janzen V, Forkert R, et al. Haploinsufficiency of GATA-2 perturbs adult hematopoietic stem-cell homeostasis[J]. Blood, 2005, 106(2): 477-484.
[25] Rodrigues NP, Boyd AS, Fugazza C, et al. GATA-2 regulates granulocyte-macrophage progenitor cell function[J]. Blood, 2008, 112(13): 4862-4873.
[26] Tong Q, Tsai J, Tan G, et al. Interaction between GATA and the C/EBP family of transcription factors is critical in GATAmediated suppression of adipocyte differentiation[J]. Mol Cell Biol, 2005, 25(2): 706-715.
[27] Hahn CN, Chong CE, Carmichael CL, et al. Heritable GATA2 mutations associated with familial myelodysplastic syndrome and acute myeloid leukemia[J]. Nature Genet, 2011, 43(10): 1012-1017.
[28] Vicente C, Vazquez I, Conchillo A, et al. Overexpression of GATA2 predicts an adverse prognosis for patients with acute myeloid leukemia and it is associated with distinct molecular abnormalities[J]. Leukemia, 2011, 26(3): 550-554.
[29] Böhm M, Locke WJ, Sutherland RL, et al. A role for GATA-2 in transition to an aggressive phenotype in prostate cancer through modulation of key androgen-regulated genes[J]. Oncogene, 2009, 28(43): 3847-3856.
[30] 吴秀丽, 李扬秋.造血转录因子GATA-2 的研究进展[J].现 代临床医学生物工程学杂志, 2003, 9(5): 387.
[31] Huang Z, Dore L C, Li Z, et al. GATA-2 reinforces megakaryocyte development in the absence of GATA-1[J]. Mol Cell Biol, 2009, 29(18): 5168-5180.
[32] Hsu AP, Johnson KD, Falcone EL, et al. GATA2 haploinsufficiency caused by mutations in a conserved intronic element leads to MonoMAC syndrome[J]. Blood, 2013, 121(19): 3830-3837.
[33] Cuellar-Rodriguez J, Gea-Banacloche J, Freeman A F, et al. Successful allogeneic hematopoietic stem cell transplantation for GATA2 deficiency[J]. Blood, 2011, 118(13): 3715-3720.