Abstract Objective To compare the clinical features of children with different clinical forms of congenital hepatic fibrosis (CHF), and provides a description of the characteristics of childhood CHF. Methods Sixty children with CHF between January 2002 and June 2015 were enrolled, including 26 children with portal hypertensive CHF (PH CHF), 3 children with cholangitic CHF, 30 children with combined portal hypertensive and cholangitic CHF (mixed CHF), and 1 child with latent forms of CHF. The medical data of 26 children with PH CHF and 30 children with mixed CHF, including gender, age, clinical manifestations, physical signs, laboratory tests and imaging characteristics, were retrospectively studied. Results Fever, jaundice and hepatomegaly were more frequently noted in children with mixed CHF than in those with PH CHF (PPPConclusions PH and mixed CHF are common forms in childhood CHF. The children with the two forms of PH usually manifest portal hypertension such as cirrhosis and hepatosplenomegaly. The liver damage may be common in children with mixed CHF.
WU Xin,DU Xiao-Rang,DING Jin-Fang et al. Clinical features of different clinical forms of childhood congenital hepatic fibrosis[J]. CJCP, 2016, 18(4): 335-339.
WU Xin,DU Xiao-Rang,DING Jin-Fang et al. Clinical features of different clinical forms of childhood congenital hepatic fibrosis[J]. CJCP, 2016, 18(4): 335-339.
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