Recent progress in clinical research on pertussis

WU Dan-Xia; CHEN Qiang; SHEN Kun-Ling

doi:10.7499/j.issn.1008-8830.2016.09.021

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Chinese Journal of Contemporary Pediatrics ›› 2016, Vol. 18 ›› Issue (9) : 897-902. DOI: 10.7499/j.issn.1008-8830.2016.09.021

REVIEW

Recent progress in clinical research on pertussis

WU Dan-Xia¹, CHEN Qiang¹, SHEN Kun-Ling²

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Abstract

Pertussis is a highly contagious respiratory disease. Despite the high vaccination coverage, re-emergence of pertussis has been reported in many countries over the past two decades. With the increase in the incidence of pertussis, there has been a shift in the epidemiological features:an increased incidence of pertussis has been noted in older children and adults, who normally lack typical clinical manifestations, and who may be easily missed according to current diagnostic references for pertussis. In order to achieve better prevention and treatment of pertussis, this review article summarized the recent research progress in the epidemiology, clinical features, etiology, diagnosis, treatment, and prevention of pertussis, particularly focusing on the diagnosis of pertussis in older children and adults.

Key words

Pertussis / Epidemiology / Clinical feature / Etiology / Diagnosis / Treatment / Prevention / Child

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WU Dan-Xia, CHEN Qiang, SHEN Kun-Ling. Recent progress in clinical research on pertussis[J]. Chinese Journal of Contemporary Pediatrics. 2016, 18(9): 897-902 https://doi.org/10.7499/j.issn.1008-8830.2016.09.021

References

[1] Chiappini E, Stival A, Galli L, et al. Pertussis re-emergence in the post-vaccination era[J]. BMC Infect Dis, 2013, 13:151-162.
[2] Matthias J, Pritchard PS, Martin SW, et al. Sustained transmission of pertussis in vaccinated, 1-5-year-old children in a preschool, Florida, USA[J]. Emerg Infect Dis, 2016, 22(2):242-246.
[3] Wood N, McIntyre P. Pertussis:review of epidemiology, diagnosis, management and prevention[J]. Paediatr Respir Rev, 2008, 9(3):201-212.
[4] Cornia PB, Hersh AL, Lipsky BA, et al. Does this coughing adolescent or adult patient have pertussis?[J]. JAMA, 2010, 304(8):890-896.
[5] Siriyakorn N, Leethong P, Tantawichien T, et al. Adult pertussis is unrecognized public health problem in Thailand[J]. BMC Infect Dis, 2016, 16:25.
[6] 王静敏, 杨永弘. 百日咳的研究现状[J]. 国外医学·流行病学传染病学分册, 2001, 28(2):67-70.
[7] Crowcroft NS, Pebody RG. Recent developments in pertussis[J]. Lancet, 2006, 367(9526):1926-1936.
[8] Cherry JD. Epidemic pertussis in 2012:the resurgence of a vaccine-preventable disease[J]. N Engl J Med, 2012, 367(9):785-787.
[9] Mooi FR, Van Der Maas NA, De Melker HE. Pertussis resurgence:waning immunity and pathogen adaptation-two sides of the same coin[J]. Epidemiol Infect, 2014, 142(4):685-694.
[10] Park S, Lee S, Seo K, et al. Epidemiological aspects of pertussis among adults and adolescents in a Korean outpatient setting:a multicenter, PCR-based study[J]. J Korean Med Sci, 2014, 29(9):1232-1239.
[11] 黄海涛, 高志刚. 百日咳再现及其应对策略的研究进展[J]. 医学综述, 2015, 21(9):1630-1632.
[12] Pimentel AM, Baptista PN, Ximenes RA, et al. Pertussis may be the cause of prolonged cough in adolescents and adults in the interepidemic period[J]. Braz J Infect Dis, 2015, 19(1):43-46.
[13] 米荣, 伏瑾, 王晓颖, 等. 迁延性咳嗽婴幼儿百日咳感染临床情况调查[J]. 中华医学杂志, 2013, 93(22):1721-1725.
[14] Stein-Zamir C, Shoob H, Abramson N, et al. The impact of additional pertussis vaccine doses on disease incidence in children and infants[J]. Vaccine, 2010, 29(2):207-211.
[15] Rohania P, Draked JM. The decline and resurgence of pertussis in the US[J]. Epidemics, 2011, 3(3-4):183-188.
[16] Mooi FR, van Loo IH, van Gent M, et al. Bordetella pertussis strains with increased toxin production associated with pertussis resurgence[J]. Emerg Infect Dis, 2009, 15(8):1206-1213.
[17] Ntezayabo B, De Serres G, Duval B. Pertussis resurgence in Canada largely caused by a cohort effect[J]. Pediatr Infect Dis J,2003, 22(1):22-27.
[18] Wendelboe AM, Van Rie A, Salmaso S, et al. Duration of immunity against pertussis after natural infection or vaccination[J]. Pediatr Infect Dis J, 2005, 24(5 Suppl):S58-S61.
[19] Mattoo S, Cherry JD. Molecular pathogenesis, epidemiology, and clinical manifestations of respiratory infections due to Bordetella pertussis and other Bordetella subspecies[J]. Clin Microbiol Rev, 2005, 18(2):326-382.
[20] 杨永弘, 马香. 小儿呼吸道感染的细菌病原[J]. 实用儿科临床杂志, 2011, 26(4):229-232.
[21] Wang K, Bettiol S, Thompson MJ, et al. Symptomatic treatment of the cough in whooping cough[]. Cochrane Database Syst Rev, 2014, (9):CD003257.
[22] Long SS, Edwards KM. Bordetella pertussis (Pertussis) and Other Species[M]//Long SS, Pickering LK, Prober CG. Principles and Practice of Pediatric Infectious Diseases. 4th ed. Printed in China:Elsevir Saunders, 2012:858-866.
[23] Long SS, Lischner HW, Deforest A, et al. Serologic evidence of subclinical pertussis in immunized children[J]. Pediatr Infect Dis J, 1990, 9(10):700-705.
[24] Long SS, Welkon CJ, Clark JL. Widespread silent transmission of pertussis in families:antibody correlates of infection and symptomatology[J]. J Infect Dis, 1990, 161(3):480-486.
[25] Heininger U, Kleemann WJ, Cherry JD, et al. A controlled study of the relationship between Bordetella pertussis infection and sudden unexpected deaths in German infants[J]. Pediatrics, 2004, 114(1):e9-e15.
[26] Hartzell JD, Blaylock JM. Whooping cough in 2014 and beyond:an update and review[J]. Chest, 2014, 146(1):205-214.
[27] Kamiya H, Otsuka N, Ando Y, et al. Transmission of Bordetella holmesii during pertussis outbreak, Japan[J]. Emerg Infect Dis, 2012, 18(7):1166-1169.
[28] Mooi FR, Bruisten S, Linde I, et al. Characterization of Bordetella holmesii isolates from patients with pertussis-like illness in The Netherlands[J]. FEMS Immunol Med Microbiol, 2012, 64(2):289-291.
[29] Tatti KM, Sparks KN, Boney KO, et al. Novel multitarget realtime PCR assay for rapid detection of Bordetella species in clinical specimens[J]. J Clin Microbiol, 2011, 49(12):4059-4066.
[30] Melvin JA, Scheller EV, Miller JF, et al. Bordetella pertussis pathogenesis:current and future challenges[J]. Nat Rev Microbiol, 2014, 12(4):274-288.
[31] Fedele G, Bianco M, Ausiello CM. The virulence factors of Bordetella pertussis:talented modulators of host immune response[J]. Arch Immunol Ther Exp (Warsz), 2013, 61(6):445-457.
[32] Paddock CD, Sanden GN, Cherry JD, et al. Pathology and pathogenesis of fatal Bordetella pertussis infection in infants[J]. Clin Infect Dis, 2008, 47(3):328-338.
[33] Hewlett EL, Bums DL, Cotter PA, et a1. Pertussis pathogenesiswhat we know and what we don't know[J]. J Infect Dis, 2014, 209(7):982-985.
[34] Smith C, Vyas H. Early infantile pertussis; increasingly prevalent and potentially fatal[J]. Eur J Pediatr, 2000, 159(12):898-900.
[35] Cherry JD, Paddock CD. Pathogenesis and histopathology of pertussis:implications for immunization[J]. Expert Rev Vaccines, 2014, 13(9):1115-1123.
[36] Berger JT, Carcillo JA, Shanley TP, et a1. Critical pertussis illness in children:a muticenter prospective cohort study[J]. Pediatr Crit Care Med, 2013, 14(4):356-365.
[37] Surridge J, Segedin ER, Grant CC. Pertussis requiring intensive care[J]. Arch Dis Child, 2007, 92(11):970-975.
[38] Cherry JD, Tan T, Wirsing von König CH, et al. Clinical definitions of pertussis:summary of a global pertussis initiative roundtable meeting, February 2011[J]. Clin Infect Dis, 2012, 54(12):1756-1764.
[39] Guiso N, Wirsing von Koenig CH, Forsyth K, et al. The global pertussis initiative:report from a round table meeting to discuss the epidemiology and detection of pertussis, Paris, France, 11-12 January 2010[J]. Vaccine, 2011, 29(6):1115-1121.
[40] Guiso N, Berbers G, Fry NK, et al. What to do an what not to do in serological diagnosis of pertussis:recommendations from EU reference laboratories[J]. Eur J Clin Microbiol Infect Dis, 2011, 30(3):307-312.
[41] Bock JM, Burtis CC, Poetker DM, et al. Serum immunoglobulin G analysis to establish a delayed diagnosis of chronic cough due to Bordetella pertussis[J]. Otolaryngol Head Neck Surg, 2012, 146(1):63-67.
[42] Heininger U. Pertussis:what the pediatric infectious disease specialist should know[J]. Pediatr Infect Dis J, 2012, 31(1):78-79.
[43] Altunaiji S, Kukuruzovic R, Curtis N, et al. Antibiotics for whooping cough (pertussis)[J]. Cochrane Database Syst Rev, 2007, (3):CD004404.
[44] Langley JM, Halperin SA, Boucher FD, et al. Azithromycin is as effective as and better tolerated than erythromycin estolate for the treatment of pertussis[J]. Pediatrics, 2004, 114(1):e96-e101.
[45] Bruss JB, Siber GR. Protective effects of pertussis immunoglobulin (P-IGIV) in the aerosol challenge model[J]. Clin Diagn Lab Immunol, 1999, 6(4):464-470.
[46] 胡云鸽, 刘泉波. 儿童百日咳247例临床特点及重症百日咳危险因素分析[J]. 中华儿科杂志, 2015, 53(9):684-689.
[47] Rocha G, Flôr-de-Lima F, Soares P, et al. Severe pertussis in newborns and young vulnerable infants[J]. Pediatr Infect Dis J, 2013, 32(10):1152-1154.
[48] McEniery JA, Delbridge RG, Reith DM. Infant pertussis deaths and the management of cardiovascular compromise[J]. J Paediatr Child Health, 2004, 40(4):230-232.
[49] Rowlands HE, Goldman AP, Harrington K, et al. Impact of rapid leukodepletion on the outcome of severe clinical pertussis in young infants[J]. Pediatrics, 2010, 126(4):e816-e827.
[50] 王静敏. 百日咳与百日咳疫苗[J]. 中华实用儿科临床杂志, 2013, 28(20):1530-1535.
[51] Xu Y, Tan Y, Asokanathan C, et al. Characterization of co-purified acellular pertussis vaccines[J]. Hum Vaccin Immunother, 2015, 11(2):421-427.
[52] 刁连东, 徐爱强, 杨永弘, 等. 百日咳免疫预防专家共识[J]. 中华流行病学杂志, 2011, 32(6):550-553.