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CJCP  2017, Vol. 19 Issue (3): 303-307    DOI: 10.7499/j.issn.1008-8830.2017.03.010
CLINICAL RESEARCH Current Issue| Next Issue| Archive| Adv Search  | 
Risk factors for allergic diseases in children aged 0-24 months in the Wuhu urban area, Anhui Province, China
WANG Shou-Gui1, ZHANG Xiang-Sheng1, ZHAO Yan-Fang2, SUN Li1, PAN Xi-Tao1, WAN Ning2
Department of Child Health Care, Wuhu Maternal and Child Health Care Hospital, Wuhu, Anhui 241000, China
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Abstract  Objective To investigate the prevalence of allergic diseases in children aged 0-24 months in the Wuhu urban area of Anhui Province and risk factors for allergic diseases. Methods Cluster random sampling was performed to select 600 children aged 0-24 months and their mothers from the Wuhu urban area, and a questionnaire survey was conducted to collect the data of disease history, family history, mothers' conditions during pregnancy, and child-rearing situation. Univariate analysis and multivariate logistic regression analysis were performed for such data. Results Among the 597 children included in the analysis, 56 (9.4%) were diagnosed with allergic diseases in the past. The univariate analysis showed that the age, use of antipyretic and analgesic drugs, a history of allergy in the father or grandparents, and the consumption of fish, shrimps, crabs, and shellfish during pregnancy were significantly associated with past allergic diseases (P < 0.05). The multivariate logistic regression analysis showed that the age and a history of allergy in the father or grandparents were positively associated with past allergic diseases (OR=4.0-4.9, 2.7, and 2.4 respectively; P < 0.05), while frequent consumption of fish, shrimps, crabs, and shellfish during pregnancy was negatively associated with past allergic diseases (OR=0.3; P < 0.05). Conclusions A family history of allergy is an independent risk factor for allergic diseases in children aged 0-24 months in the Wuhu urban area of Anhui Province, while frequent consumption of fish, shrimps, crabs, and shellfish during pregnancy is a protective factor.
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WANG Shou-Gui
ZHANG Xiang-Sheng
ZHAO Yan-Fang
SUN Li
PAN Xi-Tao
WAN Ning
Key wordsAllergic disease      Risk factor      Epidemiological investigation      Child     
Received: 09 October 2016     
Cite this article:   
WANG Shou-Gui,ZHANG Xiang-Sheng,ZHAO Yan-Fang et al. Risk factors for allergic diseases in children aged 0-24 months in the Wuhu urban area, Anhui Province, China[J]. CJCP, 2017, 19(3): 303-307.
WANG Shou-Gui,ZHANG Xiang-Sheng,ZHAO Yan-Fang et al. Risk factors for allergic diseases in children aged 0-24 months in the Wuhu urban area, Anhui Province, China[J]. CJCP, 2017, 19(3): 303-307.
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