Incidence of neonatal asphyxia and contributing factors for the develpment of severe asphyxia in Hubei Enshi Tujia and Miao Autonomous Prefecture: a multicenter study
WU Su-Ying1, PENG Fen1, DING Ting1, TAN Hong-Yan1, WU Qian1, YU Xin-Qiao2, PAN Zhi-Ping3, XIE Hong-Ling4, XIA Hong5, FEI Bao-Min6, LIU Kai-Dian7, YUAN Zuo-Fen7, TAN Cong-Rong8, JIANG Lang9, ZHANG Song-Hua10, YI Qiong11, WU Wei-Hua12, LUO Lin-Lin13, SHEN Chang-Tao14, ZHANG Jin-Fan15, HUANG Zhen-Ju16, XIA Shi-Wen17
Department of Neonatology, Hubei Maternal and Child Health Care Hospital, Wuhan 430070, China
Abstract Objective To investigate the incidence of neonatal asphyxia and possible contributing factors for the development of severe asphyxia in Hubei Enshi Tujia and Miao Autonomous Prefecture, China. Methods A total of 16 hospitals in Hubei Enshi Tujia and Miao Autonomous Prefecture were selected as research centers. A retrospective analysis was performed for the clinical data of 22294 live births in these 16 hospitals from January to December, 2016 to investigate the incidence rate of neonatal asphyxia and possible contributing factors for the development of severe asphyxia. Results Of the 22 294 neonates born alive, 733 (3.29%) were diagnosed with neonatal asphyxia, among whom 627 had mild asphyxia and 106 had severe asphyxia. The neonates with low maternal education level, maternal anemia during pregnancy, chorioamnionitis, abnormal amniotic fluid, abnormal umbilical cord, placenta previa, placental abruption, Tujia Minority, preterm birth, and low birth weight had a higher incidence of severe asphyxia (P < 0.05).Conclusions The incidence rate of neonatal asphyxia in Hubei Enshi Tujia and Miao Autonomous Prefecture is higher. Low maternal education level, maternal anemia during pregnancy, chorioamnionitis, abnormal amniotic fluid, abnormal umbilical cord, placenta previa, placental abruption, Tujia Minority, preterm birth, and low birth weight may be related to the development of severe neonatal asphyxia.
WU Su-Ying,PENG Fen,DING Ting et al. Incidence of neonatal asphyxia and contributing factors for the develpment of severe asphyxia in Hubei Enshi Tujia and Miao Autonomous Prefecture: a multicenter study[J]. CJCP, 2019, 21(1): 6-10.
WU Su-Ying,PENG Fen,DING Ting et al. Incidence of neonatal asphyxia and contributing factors for the develpment of severe asphyxia in Hubei Enshi Tujia and Miao Autonomous Prefecture: a multicenter study[J]. CJCP, 2019, 21(1): 6-10.
Xu T, Wang H, Gong L, et al. The impact of an intervention package promoting effective neonatal resuscitation training in rural China[J]. Resuscitation, 2014, 85(2):253-259.
Semba RD, de Pee S, Sun K, et al. Effect of parental formal education on risk of child stunting in Indonesia and Bangladesh:a cross-sectional study[J]. Lancet, 2008, 371(9609):322-328.
Ensing S, Abu-Hanna A, Schaaf JM, et al. Trends in birth asphyxia, obstetric interventions and perinatal mortality among term singletons:a nationwide cohort study[J]. J Matern Fetal Neonatal Med, 2015, 28(6):632-637.
