Abstract A boy, aged 5 years, was admitted due to chest pain for 4 months, right lower limb weakness for 2 months, and weakness of both lower limbs for 10 days. There were no symptoms of defecation/urination disorders or disturbance of consciousness, and the boy had upper motor neuron paralysis in both lower limbs, without cranial nerve involvement or sensory disorder. Spine magnetic resonance imaging revealed tumor in the spinal canal between cervical vertebra 6 and thoracic vertebra 2, which put pressure on the spinal cord. He was transferred to the department of neurosurgery for surgical treatment and fully recovered after tumor resection, and no recurrence was observed after 6 years of follow-up. The pathological diagnosis was clear cell meningioma (WHO grade Ⅱ). For children with chest pain and dyskinesia, spinal meningioma should be considered.
WEI Hong-Ling,LU Shan,CHANG Yan-Mei. Persistent chest pain for 4 months and progressive lower limb weakness for 2 months in a boy[J]. CJCP, 2019, 21(8): 820-823.
WEI Hong-Ling,LU Shan,CHANG Yan-Mei. Persistent chest pain for 4 months and progressive lower limb weakness for 2 months in a boy[J]. CJCP, 2019, 21(8): 820-823.
Yadav N, Pendharkar H, Kulkarni GB. Spinal cord infarction:clinical and radiological features[J]. J Stroke Cerebrovasc Dis, 2018, 27(10):2810-2821.
[2]
Ardern-Holmes S, Fisher G, North K. Neurofibromatosis type 2[J]. J Child Neurol, 2017, 32(1):9-22.
[3]
Yeh TK, Yeh J. Chest pain in pediatrics[J]. Pediatr Ann, 2015, 44(12):e274-e278.
[4]
Eliacik K, Kanik A, Bolat N, et al. Anxiety, depression, suicidal ideation, and stressful life events in non-cardiac adolescent chest pain:a comparative study about the hidden part of the iceberg[J]. Cardiol Young, 2017, 27(6):1098-1103.
[5]
Marseglia GL, Savasta S, Ravelli A, et al. Recurrent chest pain as the presenting manifestation of spinal meningioma[J]. Acta Paediatr, 1995, 84(9):1086-1088.
Wu L, Yang C, Liu T, et al. Clinical features and long-term outcomes of pediatric spinal meningiomas[J]. J Neurooncol, 2017, 133(2):347-355.
[9]
Louis DN, Perry A, Reifenberger G, et al. The 2016 World Health Organization classification of tumors of the central nervous system:a summary[J]. Acta Neuropathol, 2016, 131(6):803-820.
[10]
Linsler S, Keller C, Urbschat S, et al. Prognosis of meningiomas in the early 1970s and today[J]. Clin Neurol Neurosurg, 2016, 149:98-103.
[11]
Pant I, Gautam VKS, Kumari R, et al. Spinal tumour:primary cervical extradural meningioma at an unusual location[J]. J Spine Surg, 2017, 3(3):509-513.
[12]
Ito K, Imagama S, Ando K, et al. Discrimination between spinal extradural meningioma and both intra and extradural meningioma:case report[J]. Nagoya J Med Sci, 2017, 79(1):115-121.
[13]
Tao X, Dong J, Hou Z, et al. Clinical features, treatment, and prognostic factors of 56 intracranial and intraspinal clear cell meningiomas[J]. World Neurosurg, 2018, 111:e880-e887.
[14]
Pathmanaban ON, Sadler KV, Kamaly-Asl ID, et al. Association of genetic predisposition with solitary schwannoma or meningioma in children and young adults[J]. JAMA Neurol, 2017, 74(9):1123-1129.
[15]
Sahm F, Schrimpf D, Stichel D, et al. DNA methylation-based classification and grading system for meningioma:a multicentre, retrospective analysis[J]. Lancet Oncol, 2017, 18(5):682-694.