Clinical features and chest CT findings of coronavirus disease 2019 in infants and young children

ZHOU Yun, YANG Gen-Dong, FENG Kai, HUANG Hua, YUN Yong-Xing, MOU Xin-Yan, WANG Li-Fei

Chinese Journal of Contemporary Pediatrics ›› 2020, Vol. 22 ›› Issue (3) : 215-220.

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Chinese Journal of Contemporary Pediatrics ›› 2020, Vol. 22 ›› Issue (3) : 215-220. DOI: 10.7499/j.issn.1008-8830.2020.03.007
A TOPIC OF CHILDHOOD NOVEL CORONAVIRUS INFECTION

Clinical features and chest CT findings of coronavirus disease 2019 in infants and young children

  • ZHOU Yun, YANG Gen-Dong, FENG Kai, HUANG Hua, YUN Yong-Xing, MOU Xin-Yan, WANG Li-Fei
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Abstract

Objective To study the clinical features and chest CT findings of coronavirus disease 2019 (COVID-19) in infants and young children. Methods A retrospective analysis was performed for the clinical data and chest CT images of 9 children, aged 0 to 3 years, who were diagnosed with COVID-19 by nucleic acid detection between January 20 and February 10, 2020. Results All 9 children had an epidemiological history, and family clustering was observed for all infected children. Among the 9 children with COVID-19, 5 had no symptoms, 4 had fever, 2 had cough, and 1 had rhinorrhea. There were only symptoms of the respiratory system. Laboratory examination showed no reductions in leukocyte or lymphocyte count. Among the 9 children, 6 had an increase in lymphocyte count and 2 had an increase in leukocyte count. CT examination showed that among the 9 children, 8 had pulmonary inflammation located below the pleura or near the interlobar fissure and 3 had lesions distributed along the bronchovascular bundles. As for the morphology of the lesions, 6 had nodular lesions and 7 had patchy lesions; ground glass opacity with consolidation was observed in 6 children, among whom 3 had halo sign, and there was no typical paving stone sign. Conclusions Infants and young children with COVID-19 tend to have mild clinical symptoms and imaging findings not as typical as those of adults, and therefore, the diagnosis of COVID-19 should be made based on imaging findings along with epidemiological history and nucleic acid detection. Chest CT has guiding significance for the early diagnosis of asymptomatic children.

Key words

Coronavirus disease 2019 / Severe acute respiratory syndrome coronavirus 2 / Chest CT / Infant and young child

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ZHOU Yun, YANG Gen-Dong, FENG Kai, HUANG Hua, YUN Yong-Xing, MOU Xin-Yan, WANG Li-Fei. Clinical features and chest CT findings of coronavirus disease 2019 in infants and young children[J]. Chinese Journal of Contemporary Pediatrics. 2020, 22(3): 215-220 https://doi.org/10.7499/j.issn.1008-8830.2020.03.007

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