Abstract Objective To investigate the current status of readmission of neonates with hyperbilirubinemia and risk factors for readmission. Methods From January 2017 to December 2019, a total of 85 infants who were readmitted due to hyperbilirubinemia were enrolled as the study group. A total of 170 neonates with hyperbilirubinemia but without readmission during the same period of time were randomly selected as the control group. The medical data were compared between the two groups. Multivariate logistic regression was used to assess the risk factors for readmission due to hyperbilirubinemia. Results The readmission rate was 2.30%, and the interval between readmission and initial admission was 5 days. Compared with the control group, the study group had significantly higher levels of total bilirubin and indirect bilirubin at discharge (P < 0.05) and a significantly longer duration of phototherapy during the first hospitalization (P < 0.05). The univariate analysis showed that compared with the control group, the study group had significantly lower birth weight, gestational age, and age on initial admission (P < 0.05) and a significantly higher proportion of infants with glucose-6-phosphate dehydrogenase (G-6-PD) deficiency or hemolytic disease (P < 0.05). The multivariate analysis showed that low gestational age (OR=1.792, P < 0.05), young age on initial admission (OR=1.415, P < 0.05), and G-6-PD deficiency (OR=2.829, P < 0.05) were independent risk factors for readmission of neonates with hyperbilirubinemia. Conclusions The infants with hyperbilirubinemia who have lower gestational age, younger age on initial admission, and G-6-PD deficiency have a higher risk of readmission due to hyperbilirubinemia. It is thus important to strengthen the management during hospitalization and after discharge for these infants to prevent the occurrence of readmission.
XIAO Wan-Xiang,YANG Ting,ZHANG Lian. Current status of readmission of neonates with hyperbilirubinemia and risk factors for readmission[J]. CJCP, 2020, 22(9): 948-952.
XIAO Wan-Xiang,YANG Ting,ZHANG Lian. Current status of readmission of neonates with hyperbilirubinemia and risk factors for readmission[J]. CJCP, 2020, 22(9): 948-952.
Al-Omran A, Al-Abdi S, Al-Salam Z. Readmission for neonatal hyperbilirubinemia in an area with a high prevalence of glucose-6-phosphate dehydrogenase deficiency:a hospital-based retrospective study[J]. J Neonatal Perinatal Med, 2017, 10(2):181-189.
[5]
Westert GP, Lagoe RJ, Keskimäki I, et al. An international study of hospital readmissions and related utilization in Europe and the USA[J]. Health Policy, 2002, 61(3):269-278.
Edwards QT, Trudgeon R. Readmission rates, risk zones and demographic factors of healthy term breastfed newborns with hyperbilirubinemia:a retrospective chart review[J]. J Nurs Health Sci, 2017, 3(3):46-53.
Paul IM, Phillips TA, Widome MD, et al. Cost-effectiveness of postnatal home nursing visits for prevention of hospital care for jaundice and dehydration[J]. Pediatrics, 2004, 114(4):1015-1022.
LI Qian-Qian, DONG Xiao-Yue, QIAO Yu, YIN Yu-Jie, GAO Yan, ZHOU Jin-Jun, YANG Li, ZHU Rong-Ping, WANG Fu-Dong, WAN Jun, XU Yan, PAN Zhao-Jun, WANG Wei-Yuan, YAN Jun-Mei, HAN Shu-Ping, LU Hong-Yan, HU Yu-Hua, LI Shuang-Shuang, WANG Jin-Xiu, WU Ming-Fu, WANG Jun, DENG Xiao-Yi, YU Zhang-Bin. An investigation of severe neonatal hyperbilirubinemia in 13 hospitals of Jiangsu Province, China[J]. CJCP, 2020, 22(7): 690-695.
