新生儿B族链球菌感染流行病学和预防策略近十年来的研究进展

doi:10.7499/j.issn.1008-8830.2211140

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Abstract Currently, the main strategy for preventing neonatal group B Streptococcus (GBS) infection is prenatal screening combined with intrapartum antibiotic prophylaxis, which has effectively reduced the incidence of neonatal GBS early-onset disease. However, the burden of GBS infection is still significant. The intrapartum antibiotic prophylaxis strategy has limitations such as inducing antibiotic resistance and inability to effectively prevent GBS late-onset disease. It is crucial to develop and evaluate other prevention strategies, while paying close attention to assessing penicillin allergy in pregnant women and how to prevent GBS infection in neonates with negative maternal GBS screening. In recent years, there has been some progress in GBS vaccines and related immunological research, and the use of specific vaccines is expected to significantly reduce GBS infection in neonates.

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	Articles by authors
	GUO Meng-Yang
	GAO Wei
	YUAN Lin
	YAO Kai-Hu

Key words： Group B Streptococcus Intrapartum antibiotic prophylaxis Prevention Vaccine Neonate

Received: 25 November 2022

Corresponding Authors: Yao K-H, Email:yaokaihu@bch.com.cn E-mail: yaokaihu@bch.com.cn

Cite this article:

GUO Meng-Yang,GAO Wei,YUAN Lin et al. Recent research on the epidemiology and preventive strategies of neonatal group B Streptococcus infection in the latest decade[J]. CJCP, 2023, 25(5): 534-540.

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http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2211140 OR http://www.zgddek.com/EN/Y2023/V25/I5/534

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