生长激素激发试验和胰岛素样生长因子1水平检测对生长激素缺乏症的诊断意义和思考

doi:10.7499/j.issn.1008-8830.2308076

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Abstract The growth hormone (GH)/insulin-like growth factor 1 (IGF-1) axis is an essential component of the hypothalamic-pituitary growth hormone axis and plays a crucial role in childhood growth and development. Disruptions and abnormalities in the GH/IGF-1 signaling pathway and its pathways typically manifest as short stature in children. Children with short stature often undergo GH stimulation testing and IGF-1 level measurements to differentiate growth hormone deficiency (GHD) from other causes of growth delay. This article aims to analyze and elucidate the values of GH stimulation testing and IGF-1 measurement, providing reference for the diagnosis of GHD in children.

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	LI Tang

Key words： Growth hormone deficiency Growth hormone Insulin-like growth factor 1 Growth hormone stimulation testing Child

Received: 18 August 2023

Cite this article:

LI Tang. Diagnostic significance and considerations of growth hormone stimulation testing and insulin-like growth factor 1 in growth hormone deficiency[J]. CJCP, 2023, 25(12): 1193-1197.

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http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2308076 OR http://www.zgddek.com/EN/Y2023/V25/I12/1193

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