早产小于胎龄儿校正0~24月龄追赶生长的纵向研究

doi:10.7499/j.issn.1008-8830.2307059

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Abstract Objective To understand the growth and development status and differences between small for gestational age (SGA) and appropriate for gestational age (AGA) preterm infants during corrected ages 0-24 months, and to provide a basis for early health interventions for preterm infants. Methods A retrospective study was conducted, selecting 824 preterm infants who received regular health care at the Guangzhou Women and Children's Medical Center from July 2019 to July 2022, including 144 SGA and 680 AGA infants. The growth data of SGA and AGA groups at birth and corrected ages 0-24 months were analyzed and compared. Results The SGA group had significantly lower weight and length than the AGA group at corrected ages 0-18 months (P<0.05), while there were no significant differences between the two groups at corrected age 24 months (P>0.05). At corrected age 24 months, 85% (34/40) of SGA and 79% (74/94) of AGA preterm infants achieved catch-up growth. Stratified analysis by gestational age showed that there were significant differences in weight and length at corrected ages 0-9 months between the SGA subgroup with gestational age <34 weeks and the AGA subgroups with gestational age <34 weeks and ≥34 weeks (P<0.05). In addition, the weight and length of the SGA subgroup with gestational age ≥34 weeks showed significant differences compared to the AGA subgroups with gestational age <34 weeks and ≥34 weeks at corrected ages 0-18 months and corrected ages 0-12 months, respectively (P<0.05). Catch-up growth for SGA infants with gestational age <34 weeks and ≥34 weeks mainly occurred at corrected ages 0-12 months and corrected ages 0-18 months, respectively. Conclusions SGA infants exhibit delayed early-life physical growth compared to AGA infants, but can achieve a higher proportion of catch-up growth by corrected age 24 months than AGA infants. Catch-up growth can be achieved earlier in SGA infants with a gestational age of <34 weeks compared to those with ≥34 weeks.

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	LI Jia-Mei
	XIE Qun-Ying
	WEN Yu-Qi
	SONG Yan-Yan
	LIANG Hui-Ying
	HU Yan

Key words： Small for gestational age Appropriate for gestational age Physical growth Catch-up growth Preterm infant

Received: 08 July 2023

Cite this article:

LI Jia-Mei,XIE Qun-Ying,WEN Yu-Qi et al. Longitudinal study on catch-up growth in preterm infants with small for gestational age at corrected ages 0-24 months[J]. CJCP, 2024, 26(1): 72-80.

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http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2307059 OR http://www.zgddek.com/EN/Y2024/V26/I1/72

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