青春期矮身材儿童身高改善的药物治疗

doi:10.7499/j.issn.1008-8830.2309125

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Abstract Short stature in puberty significantly affects the physical and mental health of adolescents. The continuous acceleration of skeletal maturation, caused by sex hormones during puberty, limits the time available for growth and poses a considerable challenge for the treatment of short stature. To date, there is still no standardized treatment protocol for this disorder. However, puberty is the last period to improve the final adult height. Currently, commonly used pharmacological treatments in clinical settings include recombinant human growth hormone, gonadotropin-releasing hormone analogs, and third-generation aromatase inhibitors. In recent years, personalized treatment aiming to improve the final adult height has become a key focus in clinical practice. This article provides a comprehensive summary of research on pharmacological therapies for height improvement in pubertal children with short stature, offering valuable insights for healthcare professionals.

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	ZHU Jian-Fang
	WANG Chun-Lin

Key words： Short stature Recombinant human growth hormone Gonadotropin-releasing hormone analog Aromatase inhibitor Puberty

Received: 21 September 2023

Cite this article:

ZHU Jian-Fang,WANG Chun-Lin. Pharmacological therapies for height improvement in pubertal children with short stature[J]. CJCP, 2024, 26(2): 118-123.

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http://www.zgddek.com/EN/10.7499/j.issn.1008-8830.2309125 OR http://www.zgddek.com/EN/Y2024/V26/I2/118

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