Abstract OBJECTIVE: To study the diagnosis, surgical treatment and outcome of craniopharyngioma in 31 children.MethodsThe clinical data of 31 children (aged 7-14 years) with craniopharyngioma were studied retrospectively. RESULTS: Headache, visusal disorder and growth retardation were main manifestations in the 31 children. The 31 children were definitely diagnosed with craniopharyngioma by CT and MRI. In the 31 cases, 19 (61.3%) underwent total tumor removal, 5 (16.1%) subtotal removal, and 7 (22.6%) partial removal. After tumor removal, transient diabetes insipidus occurred in 19 cases (61.3%) and long-term diabetes insipidus in 3 cases. Six cases (19.4%) presented hypothalamic injuries after surgery. No patient died after surgery. Five patients (16.1%) had recurrent tumor in a mean follow-up of 32.5 months.ConclusionsThe diagnosis of childhood craniopharyngioma may be based on clinical manifestations and CT/MRI examinations. Craniotomy is a preferred surgical treatment. Proper extent of tumor resection should be determined in order to reduce the tumor recurrence and the incidence of postoperative complications.［Chin J Contemp Pediatr, 2009, 11 (8):663-665］
LIU Zhi-Xiong,LIU Yun-Sheng,YUAN Xian-Rui et al. Surgical treatment of childhood craniopharyngioma: clinical analysis of 31 cases[J]. 中国当代儿科杂志, 2009, 11(08): 663-665.
LIU Zhi-Xiong,LIU Yun-Sheng,YUAN Xian-Rui et al. Surgical treatment of childhood craniopharyngioma: clinical analysis of 31 cases[J]. CJCP, 2009, 11(08): 663-665.
［4］Puget S, Garnett M, Wray A, Grill J, Habrand JL, Bodaert N, et al. Pediatric craniopharyngiomas:classification and treatment according to the degree of hypothalamic involvement［J］. J Neurosurg, 2007,106(1 Suppl):3-12.
［5］Elliott RE, Wisoff JH. Successful surgical treatment of craniopharyngioma in very young children［J］. J Neurosurg Pediatr, 2009, 3(5):397-406.
［9］Yasargil MG, Curcic M, Kis M, Siegenthaler G, Teddy PJ, Roth P. Total removal of craniopharyngiomas.Approaches and long-term results in 144 patients［J］.J Neurosurg, 1990, 73(1):3-11.
［10］Karavitaki N, Brufani C, Warner JT, Adams CB, Richards P, Ansorge O, et al. Craniopharyngiomas in children and adults: systematic analysis of 121 cases with long-term follow-up［J］. Clin Endocrinol (Oxf), 2005, 62(4):397-409.
