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| Heme oxygenase-1 and oxidative stress |
| XU Xiao-Zhi, HE Ping. |
| Department of Pediatrics, Second hospital Affiliated to Kunming Medical College, Kunming 650031, China. |
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| ［1］Ryter SW, Alam J, Choi AM. Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications［J］. Physiol Rev, 2006, 86（2）:583-650.
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| ［2］李俊，黄艳.血红素加氧酶-1的研究进展［J］.安徽医药，2005，9（1）：3-7.
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| ［3］Tremellen K. Oxidative stress and male infertility-a clinical perspective［J］. Hum Reprod Update, 2008, 14(3):243-258.
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| ［4］Kowluru RA, Chan PS. Oxidative stress and diabetic retinopathy［J］. Exp Diabetes Res, 2007, 2007:43603.
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| ［5］Parfenova H, Basuroy S, Bhattacharya S, Tcheranova D, Qu Y, Regan RF, et al. Glutamate induces oxidative stress and apoptosis in cerebral vascular endothelial cells: contributions of HO-1 and HO-2 to cytoprotection［J］. Am J Physiol Cell Physiol, 2006, 290(5): C1399-C1410.
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| ［6］Milbury PE, Graf B, Curran-Celentano JM, Blumberg JB. Bilberry (Vaccinium myrtillus) anthocyanins modulate heme oxygenase-1 and glutathione S-transferase-pi expression in ARPE-19 cells［J］. Invest Ophthalmol Vis Sci, 2007, 48(5):2343-2349.
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| ［7］Xue H, Guo H, Li YC, Hao ZM. Heme oxygenase-1 induction by hemin protects liver cells from ischemia/reperfusion injury in cirrhotic rats［J］. World J Gastroenterol, 2007, 13(40): 5384-5390.
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| ［8］Sheftel AD, Kim SF, Ponka P. Nonheme induction of heme oxygenase-1 does not alter cellular iron metabolism［J］.J Biol Chem, 2007, 282(14):10480-10486.
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| ［9］Morita T. Heme oxygenase and atherosclerosis［J］. Arterioscler, Thromb Vasc Biol, 2005, 25(9):1786-1795.
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| ［10］Sato T, Takeno M, Honma K, Yamauchi H, Saito Y, Sasaki T. Heme oxygenase-1, a potential biomarker of chronic silicosis, attenuates silicainduced lung injury［J］. Am J Respir Crit Care Med, 2006, 174(8):906-914.
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| ［11］Brydun A, Watari Y, Yamamoto Y, Okuhara k, Teragawa H, Kono F,et al. Reduced expression of heme oxygenase-1 in patients with coronary atherosclerosis［J］. Hypertens Res, 2007, 30(4):341-348.
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| ［12］Lin Q, Weis S, Yang G, Weng YH, Helston R, Rish K, et al. Heme oxygenase-1 protein localizes to the nucleus and activates transcription factors important in oxidative stress［J］.J Biol Chem, 2007, 282(28):20621-20633.
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| ［13］Ryter SW, Morse D, Choi AM. Carbon monoxide and bilirubin: potential therapies for pulmonary/vascular injury and disease［J］. Am J Respir Cell Mol Biol, 2007, 36(2):175-182.
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| ［14］刘少华，马可，许兵，徐鑫荣.一氧化碳吸入对脂多糖诱导大鼠急性肺损伤的保护作用（英文）［J］. 生理学报, 2006, 58 (5): 483-489.
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| ［15］Foresti R, Bains S, Sulc F, Farmer PJ, Green CJ, Motterlini R. The interaction of nitric oxide with distinct hemoglobins differentially amplifies endothelial heme uptake and heme oxygenase-1 expression［J］. J Pharmacol Exp Ther, 2006, 317(3):1125-1133.
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| ［16］Otterbein L, Chin BY, Otterbein SL, Lowe VC, Fessler HE, Choi AM. Mechanism of hemoglobin-induced protection against endotoxemia in rats: a ferritin-independent pathway［J］. Am J Physiol, 1997, 272(2 Pt 1):L268-L275.
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| ［17］赵卉，井军虎，李建强，刘卓拉.胆红素在大鼠肺脏缺血再灌注损伤中的抗凋亡作用［J］.中国药物与临床，2007，7（9）：677-680.
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| ［18］Inguaggiato P, Gonzalez-Michaca L, Croatt AJ, Haggard JJ, Alam J, Nath KA.Cellular overexpression of heme oxygenase-1 up-regulates p21 and confers resistance to apoptosis ［J］. Kidney Int, 2001, 60（6）：2181-2191.
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| ［19］Tang YL, Tang Y, Zhang YC, Qian K, Shen L, Phillips MI. Protection from ischemic heart injury by a vigilant heme oxygenase-1 plasmid system［J］. Hypertension, 2004, 43(4):746-751.
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| ［20］Soares MP, Usheva A, Brouard S, Berberat PO, Gunther L, Tobiasch E, et al. Modulation of endothelial cell apoptosis by heme oxygenase-1derived carbon monoxide［J］. Antioxid Redox Signal, 2002, 4(2):321-329.
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| ［21］Choi BM, Pae HO, Jeong YR, Oh GS, Jun CD, Kim BR, et al. Overexpression of heme oxygenase (HO)-1 renders Jurkat T cells resistant to fasmediated apoptosis: involvement of iron released by HO-1［J］. Free Radic Biol Med, 2004, 36(7):858-871.
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| ［22］李建强，高晓玲，刘卓拉，徐永健，张珍祥。胆红素对急性肺损伤大鼠肺血管内皮细胞核因子κB，细胞间粘附分子1表达的影响［J］.中国组织化学与细胞化学杂志, 2004, 13（1）：1-5.
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| ［23］Coito AJ, Buelow R, Shen XD, Amersi F, Moore C, Volk HD, et al . Heme oxygenase-1 gene transfer inhibits inducible nitric oxide synthase expression and protects genetically fat Zucker rat livers from ischemia-reperfusion injury ［J］. Transplantation, 2002, 74(1):96-102.
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| ［24］林宇，郭恒怡.血红素加氧酶和一氧化氮合酶在缺血性脑损伤时的保护作用［J］.国外医学脑血管分册, 2005, 13（8）：596-599.
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| ［25］Kitamuro T, Takahashi K, Ogawa K, Udono-Fujimori R, Takeda K, Furuyama K, et al. Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells［J］. J Biol Chem, 2003, 278(11): 9125-9133.
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