重视早产儿早发型败血症的抗生素准确使用

余加林

doi:10.7499/j.issn.1008-8830.2020.01.002

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中国当代儿科杂志 ›› 2020, Vol. 22 ›› Issue (1) : 7-8. DOI: 10.7499/j.issn.1008-8830.2020.01.002

述评

重视早产儿早发型败血症的抗生素准确使用

余加林

作者信息 +

Accurate use of antibiotics for preterm infants with early-onset sepsis should be taken seriously

YU Jia-Lin

Author information +

文章历史 +

摘要

早产儿早发型败血症（EOS）的抗生素应用不规范目前在我国是普遍现象，湖南省新生儿科专家制定了关于早产儿早发型败血症的诊断与抗生素使用的专家共识[中国当代儿科杂志，2020，22（1）：1-6]，对业内抗生素的规范使用有积极作用。基于此共识建议，该述评提出，要准确使用抗生素，首先必须准确识别早产儿EOS，对其临床表现和病史需准确认识，实验室检查结果需准确评价，并对早产儿EOS抗生素的使用提出了建议。

Abstract

At present, non-standard use of antibiotics remains a common phenomenon in the treatment of preterm infants with early-onset sepsis (EOS) in China. The expert panel of neonatologists in Hunan Province formulated a consensus on the diagnosis and use of antibiotics for EOS in preterm infant

导出引用

余加林. 重视早产儿早发型败血症的抗生素准确使用[J]. 中国当代儿科杂志. 2020, 22(1): 7-8 https://doi.org/10.7499/j.issn.1008-8830.2020.01.002

YU Jia-Lin. Accurate use of antibiotics for preterm infants with early-onset sepsis should be taken seriously[J]. Chinese Journal of Contemporary Pediatrics. 2020, 22(1): 7-8 https://doi.org/10.7499/j.issn.1008-8830.2020.01.002

参考文献

[1] 中华医学会儿科学分会新生儿学组, 中国医师协会新生儿科医师分会感染专业委员会. 新生儿败血症诊断及治疗专家共识(2019年版)[J]. 中华儿科杂志, 2019, 57(4):252-257.
[2] Puopolo KM, Benitz WE, Zaoutis TE, et al. Management of neonates born at ≤ 346/7 weeks' gestation with suspected or proven early-onset bacterial sepsis[J]. Pediatrics, 2018, 142(6). piie20182896.
[3] Mukhopadhyay S, Puopolo KM. Clinical and microbiologic characteristics of early-onset sepsis among very low birth weight infants:opportunities for antibiotic stewardship[J]. Pediatr Infect Dis J, 2017, 36(5):477-481.
[4] He Y, Chen J, Liu Z, et al. Efficacy and safety of applying a neonatal early-onset sepsis risk calculator in China[J]. J Paediatr Child Health, 2019:doi:10.1111/jpc.14572.[Epub ahead of print].
[5] Carola D, Vasconcellos M, Sloane A, et al. Utility of early-onset sepsis risk calculator for neonates born to mothers with chorioamnionitis[J]. J Pediatr, 2018, 195:48-52.
[6] Polin RA, Watterberg K, Benitz W, et al. The conundrum of early-onset sepsis[J]. Pediatrics, 2014, 133(6):1122-1123.
[7] Bernhard R, Renoldner B, Hofer N. Comparison between pathogen associated laboratory and clinical parameters in early-onset sepsis of the newborn[J]. Open Microbiol J, 2016, 10:133-139.
[8] Stocker M, Fontana M, El Helou S, et al. Use of procalcitonin-guided decision-making to shorten antibiotic therapy in suspected neonatal early-onset sepsis:prospective randomized intervention trial[J]. Neonatology, 2010, 97(2):165-174.