加强儿童奥密克戎感染的防治

焦富勇, 马蕾

中国当代儿科杂志 ›› 2022, Vol. 24 ›› Issue (4) : 345-349.

PDF(504 KB)
HTML
PDF(504 KB)
HTML
中国当代儿科杂志 ›› 2022, Vol. 24 ›› Issue (4) : 345-349. DOI: 10.7499/j.issn.1008-8830.2201001
专家讲座

加强儿童奥密克戎感染的防治

  • 焦富勇, 马蕾
作者信息 +

Strengthening the prevention and treatment of Omicron infection in children

  • JIAO Fu-Yong, MA Lei
Author information +
文章历史 +

摘要

奥密克戎(Omicron)是近来新发现的一种新型冠状病毒肺炎新型变异病毒,迅速在全球传播,被世界卫生组织定为需要关注的变种(variant of concern),其流行病学、致病特点、临床诊断、治疗和预防仍在观察与总结中,儿童感染后的诊疗报道更少。该文就奥密克戎感染对儿童的影响、预防、诊断和治疗进行介绍。 引

Abstract

Omicron is a newly discovered variant virus of coronavirus disease 2019 and has spread rapidly around the world. Omicron has been defined as a variant of concern by the World Health Organization. Its epidemiology, pathogenic characteristics, clinical diagnosis, treatment, and prevention are still being observed and summarized, and in particular, there are few reports on the diagnosis and treatment of children with Omicron infection. This article introduces the influence of Omicron infection in children and its prevention, diagnosis, and treatment.

关键词

新型冠状病毒肺炎 / 奥密克戎 / 预防 / 治疗 / 儿童

Key words

Coronavirus disease 2019 / Omicron / Prevention / Treatment / Child

引用本文

导出引用
焦富勇, 马蕾. 加强儿童奥密克戎感染的防治[J]. 中国当代儿科杂志. 2022, 24(4): 345-349 https://doi.org/10.7499/j.issn.1008-8830.2201001
JIAO Fu-Yong, MA Lei. Strengthening the prevention and treatment of Omicron infection in children[J]. Chinese Journal of Contemporary Pediatrics. 2022, 24(4): 345-349 https://doi.org/10.7499/j.issn.1008-8830.2201001

参考文献

1 Centers for Disease Control and Prevention. New SARS-CoV-2 variant of concern identified: Omicron (B.1.1.529) variant[EB/OL]. (2021-12-01)[2022-03-05]. https://emergency.cdc.gov/han/2021/han00459.asp.
2 Bittmann S. Role of Omicron variant of SARS-CoV-2 in children in Germany[J]. World J Pediatr, 2022. Epub ahead of print. PMID: 35103906. PMCID: PMC8804670. DOI: 10.1007/s12519-021-00511-3.
3 Viana R, Moyo S, Amoako DG, et al. Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa[J]. Nature, 2022. Epub ahead of print. PMID: 35042229. DOI: 10.1038/s41586-022-04411-y.
4 Centers for Disease Control and Prevention. Omicron variant: what you need to know[EB/OL]. (2021-12-01)[2022-03-04]. https://www.cdc.gov/coronavirus/2019-ncov/variants/omicron-variant.html.
5 Kupferschmidt K, Vogel G. How bad is Omicron? Some clues are emerging[J]. Science, 2021, 374(6573): 1304-1305. PMID: 34882443. DOI: 10.1126/science.acx9782.
6 Jiao F, Wang J, Wang C. Strengthening prevention of Omicron infection[J]. J Bio Innov, 2022, 11(1): 221-223. DOI: 10.46344/JBINO.2022.v11i01.22.
7 World Health Organization. Enhancing response to Omicron SARS-CoV-2 variant[EB/OL]. (2022-01-21)[2022-03-06]. https://www.who.int/publications/m/item/enhancing-readiness-for-omicron-(b.1.1.529)-technical-brief-and-priority-actions-for-member-states.
8 Backer JA, Eggink D, Andeweg SP, et al. Shorter serial intervals in SARS-CoV-2 cases with Omicron BA.1 variant compared with Delta variant, the Netherlands, 13 to 26 December 2021[J]. Euro Surveill, 2022, 27(6): 2200042. PMID: 35144721. PMCID: PMC8832521. DOI: 10.2807/1560-7917.ES.2022.27.6.2200042.
9 Zhou H, Tada T, Dcosta BM, et al. Neutralization of SARS-CoV-2 Omicron BA.2 by therapeutic monoclonal antibodies[J]. bioRxiv[Preprint]. (2022-02-24)[2022-03-08]. PMID: 35194604. PMCID: PMC8863139. DOI: 10.1101/2022.02.15.480166.
10 Gobeil SM, Henderson R, Stalls V, et al. Structural diversity of the SARS-CoV-2 Omicron spike[J]. bioRxiv[Preprint]. (2022-01-26)[2022-03-09]. PMID: 35118469. PMCID: PMC8811902. DOI: 10.1101/2022.01.25.477784.
11 Wang L, Berger NA, Kaelber DC, et al. Comparison of outcomes from COVID infection in pediatric and adult patients before and after the emergence of Omicron[J]. medRxiv[Preprint]. (2022-01-02) [2022-03-09]. PMID: 35018384. PMCID: PMC8750707. DOI: 10.1101/2021.12.30.21268495.
12 Omotuyi O, Olubiyi O, Nash O, et al. SARS-CoV-2 Omicron spike glycoprotein receptor binding domain exhibits super-binder ability with ACE2 but not convalescent monoclonal antibody[J]. Comput Biol Med, 2022, 142: 105226. PMID: 35066447. PMCID: PMC8739363. DOI: 10.1016/j.compbiomed.2022.105226.
13 Pulliam JRC, van Schalkwyk C, Govender N, et al. Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa[J]. medRxiv[Preprint]. (2022-03-06)[2022-03-08]. DOI: 10.1101/2021.11.11.21266068.
14 Khoury DS, Steain M, Triccas JA, et al. A meta-analysis of early results to predict vaccine efficacy against Omicron[J]. medRxiv[Preprint]. (2021-12-17)[2022-03-08]. DOI: 10.1101/2021.12.13.21267748.
15 Doria-Rose NA, Shen X, Schmidt SD, et al. Booster of mRNA-1273 strengthens SARS-CoV-2 omicron neutralization[J]. medRxiv[Preprint]. (2021-12-20)[2022-03-06]. PMID: 34931200. PMCID: PMC8687471. DOI: 10.1101/2021.12.15.21267805.
16 Syed AM, Ciling A, Khalid MM, et al. Omicron mutations enhance infectivity and reduce antibody neutralization of SARS-CoV-2 virus-like particles[J]. medRxiv[Preprint]. (2022-01-02) [2022-03-07]. PMID: 34981067. PMCID: PMC8722610. DOI: 10.1101/2021.12.20.21268048.
17 Centers for Disease Control and Prevention. Covid data tracker weekly review[EB/OL]. (2022-02-11)[2022-03-05]. https://www.cdc.gov/coronavirus/2019-ncov/covid-data/covidview/.
18 Lima DGS, Figueiredo TMR, Pereira YTG, et al. The effects of the silence on south African children and adolescents against a global alert on the newly identified coronavirus variant: Omicron[J]. J Pediatr Nurs, 2021. Epub ahead of print. PMID: 34930655. DOI: 10.1016/j.pedn.2021.11.032.
19 European Centre for Disease Prevention and Control. Assessment of the further emergence of the SARS-CoV-2 Omicron VOC in the context of the ongoing Delta VOC transmission in the EU/EEA, 18th update[EB/OL]. (2021-12-15)[2022-03-06]. https://www.ecdc.europa.eu/en/publications-data/covid-19-assessment-further-emergence-omicron-18th-risk-assessment.
20 国家卫生健康委员会宣传司. 关于奥密克戎, 国家卫生健康委最新解答来了![EB/OL]. (2022-01-17)[2022-03-15]. http://www.nhc.gov.cn/xcs/s7847/202201/1c1a23e9e172481da9a6b087c3eaa8fe.shtml.
21 World Health Organization. Update on Omicron[EB/OL]. (2021-11-28)[2022-03-04]. https://www.who.int/news/item/28-11-2021-update-on-omicron.
22 世界卫生组织. 儿童和青少年的COVID-19疾病[EB/OL]. (2021-09-29)[2022-03-02]. https://apps.who.int/iris/bitstream/handle/10665/345575/WHO-2019-nCoV-Sci-Brief-Children-and-adolescents-2021.1-chi.pdf.
23 Li Ka Shing Faculty of Medicine, The University of Hong Kong. HKUMed finds Omicron SARS-CoV-2 can infect faster and better than Delta in human bronchus but with less severe infection in lung[EB/OL]. (2021-12-15)[2022-03-06]. https://www.med.hku.hk/en/news/press/20211215-omicron-sars-cov-2-infection.
24 Ludvigsson JF. Convulsions in children with COVID-19 during the Omicron wave[J]. Acta Paediatr, 2022. Epub ahead of print. PMID: 35098577. DOI: 10.1111/apa.16276.
25 World Health Organization. Antigen-detection in the diagnosis of SARS-CoV-2 infection: Interim guidance[EB/OL]. (2021-10-06)[2022-03-05]. https://www.who.int/publications/i/item/antigen-detection-in-the-diagnosis-of-sars-cov-2infection-using-rapid-immunoassays.
26 陈志敏, 傅君芬, 舒强, 等. 儿童2019冠状病毒病(COVID-19)诊疗指南(第二版)[J]. 浙江大学学报(医学版), 2020, 49(2): 139-146. DOI: 10.3785/j.issn.1008-9292.2020.02.01.
27 世界卫生组织. 疗法与2019冠状病毒病: 动态指南[EB/OL]. (2021-12-07)[2022-03-09]. https://apps.who.int/iris/bitstream/handle/10665/350177/WHO-2019-nCoV-therapeutics-2021.4-chi.pdf.
28 《天津市儿童新型冠状病毒肺炎中医诊疗方案(试行第一版)》制定专家组. 天津市儿童新型冠状病毒肺炎中医诊疗方案(试行第一版)[J]. 天津中医药, 2022, 39(2): 137-138. DOI: 10.11656/j.issn.1672-1519.2022.02.01
29 Queen D. Another year another variant: COVID 3.0-Omicron[J]. Int Wound J, 2022, 19(1): 5. PMID: 34927365. PMCID: PMC8684846. DOI: 10.1111/iwj.13739.

PDF(504 KB)
HTML

Accesses

Citation

Detail

段落导航
相关文章

/