急性淋巴细胞白血病儿童认知功能损害的临床研究进展

覃李娇, 麦惠容

中国当代儿科杂志 ›› 2023, Vol. 25 ›› Issue (3) : 315-320.

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中国当代儿科杂志 ›› 2023, Vol. 25 ›› Issue (3) : 315-320. DOI: 10.7499/j.issn.1008-8830.2210063
综述

急性淋巴细胞白血病儿童认知功能损害的临床研究进展

  • 覃李娇, 麦惠容
作者信息 +

Recent research on cognitive impairment in children with acute lymphoblastic leukemia

  • QIN Li-Jiao, MAI Hui-Rong
Author information +
文章历史 +

摘要

急性淋巴细胞白血病(acute lymphoblastic leukemia,ALL)是儿童期最常见的恶性肿瘤性疾病。随着临床诊治水平的不断提高,获得完全缓解后长期生存的ALL儿童越来越多,其中相当部分患儿都存在认知功能损害,并对学习、就业和社交活动产生严重的不良影响。该文从ALL患儿认知功能损害的影响因素、检测技术的应用及预防与治疗对ALL患儿认知损害的临床研究进展进行综述。

Abstract

Acute lymphoblastic leukemia (ALL) is the most common malignant neoplastic disease in children. With the continuous improvement in diagnosis and treatment, there has been an increasing number of ALL children who achieve long-term survival after complete remission; however, a considerable proportion of these children have cognitive impairment, which has a serious adverse impact on their learning, employment, and social life. This article reviews the latest research on cognitive impairment in children with ALL from the aspects of the influencing factors, detection techniques, and prevention/treatment methods for cognitive impairment.

关键词

急性淋巴细胞白血病 / 认知功能 / 影响因素 / 儿童

Key words

Acute lymphoblastic leukemia / Cognitive function / Influencing factor / Child

引用本文

导出引用
覃李娇, 麦惠容. 急性淋巴细胞白血病儿童认知功能损害的临床研究进展[J]. 中国当代儿科杂志. 2023, 25(3): 315-320 https://doi.org/10.7499/j.issn.1008-8830.2210063
QIN Li-Jiao, MAI Hui-Rong. Recent research on cognitive impairment in children with acute lymphoblastic leukemia[J]. Chinese Journal of Contemporary Pediatrics. 2023, 25(3): 315-320 https://doi.org/10.7499/j.issn.1008-8830.2210063

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基金

广东省基础与应用基础研究基金(2020A1515010246);广东省高水平医院建设专项经费资助;深圳市高水平医院建设专项经费资助;深圳市医学重点学科建设经费资助(SZXK034)。

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