儿童急性肝衰竭的诊治进展

明慧; 何怡; 许红梅

doi:10.7499/j.issn.1008-8830.2309015

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中国当代儿科杂志 ›› 2024, Vol. 26 ›› Issue (2) : 194-200. DOI: 10.7499/j.issn.1008-8830.2309015

综述

儿童急性肝衰竭的诊治进展

明慧, 何怡, 许红梅

作者信息 +

Advancements in the diagnosis and treatment of pediatric acute liver failure

MING Hui, HE Yi, XU Hong-Mei

Author information +

文章历史 +

摘要

儿童急性肝衰竭（pediatric acute liver failure, PALF）是一种罕见、病情进展迅速的临床综合征，预后较差，病死率非常高。PALF病因复杂，临床表现多样且不典型，基于年龄的病因诊断、肝性脑病的早期识别、预防及精准的对因支持治疗对改善结局和预后至关重要。该文主要总结PALF诊断及治疗的相关进展，以期为临床工作提供帮助。

Abstract

Pediatric acute liver failure (PALF) is a rare and rapidly progressive clinical syndrome with a poor prognosis and significant mortality. The etiology of PALF is complex, and it presents with diverse and atypical clinical manifestations. Accurate diagnosis based on age-related factors, early recognition or prevention of hepatic encephalopathy, and precise supportive treatment targeting the underlying cause are crucial for improving outcomes and prognosis. This article provides a comprehensive review of recent research on the diagnosis and treatment of PALF, aiming to offer guidance for clinical practice.

导出引用

明慧, 何怡, 许红梅. 儿童急性肝衰竭的诊治进展[J]. 中国当代儿科杂志. 2024, 26(2): 194-200 https://doi.org/10.7499/j.issn.1008-8830.2309015

MING Hui, HE Yi, XU Hong-Mei. Advancements in the diagnosis and treatment of pediatric acute liver failure[J]. Chinese Journal of Contemporary Pediatrics. 2024, 26(2): 194-200 https://doi.org/10.7499/j.issn.1008-8830.2309015

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