中国儿童川崎病诊疗循证指南（2023年）

doi:10.7499/j.issn.1008-8830.2309038

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中国当代儿科杂志 ›› 2023, Vol. 25 ›› Issue (12) : 1198-1210. DOI: 10.7499/j.issn.1008-8830.2309038

标准·方案·指南

中国儿童川崎病诊疗循证指南（2023年）

陕西省川崎病诊疗中心/陕西省人民医院儿童病院,国家儿童医学中心/首都医科大学附属北京儿童医院,上海交通大学医学院附属儿童医院,国家区域医疗中心/中国医科大学附属盛京医院,国家临床重点专科/上海市儿童医院重症医学科,中国医师协会儿科医师分会普儿科学组,中国妇幼健康研究会儿科能力建设专家委员会,国家卫生健康委员会热带病防治重点实验室,延安大学附属医院,《中国当代儿科杂志》编辑部

作者信息 +

Evidence-based guidelines for the diagnosis and treatment of Kawasaki disease in children in China (2023)

Center for Diagnosis and Treatment of Kawasaki Disease/Children's Hospital of Shaanxi Provincial People's Hospital, National Children's Medical Center/Beijing Children's Hospital, Capital Medical University, Children's Hospital, Shanghai Jiao Tong University School of Medicine, National Regional Medical Center/Shengjing Hospital of China Medical University, National Clinical Key Specialty/Department of Intensive Care Medicine, Shanghai Children's Hospital, General Pediatric Group of Pediatrician Branch of Chinese Medical Doctor Association, Expert Committee of Advanced Training for Pediatrician, China Maternal and Children's Health Association, National Health Commission Key Laboratory for Tropical Disease Prevention and Control, Yan'an University Affiliated Hospital, Editorial Department of Chinese Journal of Contemporary Pediatrics

Author information +

文章历史 +

摘要

川崎病（Kawasaki disease, KD）是一种急性自限性血管炎性疾病，是引起5岁以下儿童后天获得性心脏病的最常见原因。国家卫生健康委员会发布的2023年儿科质控工作改进目标之一是降低KD患儿心脏事件的发生率及KD相关病死率。为规范我国KD的诊断、治疗和长期管理实践，有效预防、减少冠状动脉病变的发生及远期不良影响，指南工作组遵循世界卫生组织指南制订的原则和方法，参照现有国内外证据和经验形成了《中国儿童川崎病诊疗循证指南（2023年）》。该指南针对KD的分类及定义、不同类型KD的诊断、KD急性期治疗、超声心动图在KD并发症识别中的应用和KD合并巨噬细胞活化综合征的处理等临床问题，基于最佳证据和专家共识形成了20条推荐意见，以期为广大医护人员在儿童KD的诊断与治疗方面提供指导与决策依据。

Abstract

Kawasaki disease (KD) is an acute self-limiting vasculitis, and it is the most common cause of acquired heart disease in children under 5 years old. One of the improvement goals in pediatric quality control work for the year 2023, as announced by the National Health Commission, is to reduce the incidence of cardiac events and KD-related mortality in children with KD. In order to standardize the diagnosis, treatment, and long-term management practices of KD in China, and effectively prevent and reduce the incidence of coronary artery lesions and long-term adverse effects, the guideline working group followed the principles and methods outlined by the World Health Organization and referenced existing evidence and experiences to develop the "Evidence-based guidelines for the diagnosis and treatment of Kawasaki disease in children in China (2023)". The guidelines address the clinical questions regarding the classification and definition of KD, diagnosis of different types of KD, treatment during the acute phase of KD, application of echocardiography in identifying complications of KD, and management of KD combined with macrophage activation syndrome. Based on the best evidence and expert consensus, 20 recommendations were formulated, aiming to provide guidance and decision-making basis for healthcare professionals in the diagnosis and treatment of KD in children.

导出引用

陕西省川崎病诊疗中心/陕西省人民医院儿童病院,国家儿童医学中心/首都医科大学附属北京儿童医院,上海交通大学医学院附属儿童医院,国家区域医疗中心/中国医科大学附属盛京医院,国家临床重点专科/上海市儿童医院重症医学科,中国医师协会儿科医师分会普儿科学组,中国妇幼健康研究会儿科能力建设专家委员会,国家卫生健康委员会热带病防治重点实验室,延安大学附属医院,《中国当代儿科杂志》编辑部. 中国儿童川崎病诊疗循证指南（2023年）[J]. 中国当代儿科杂志. 2023, 25(12): 1198-1210 https://doi.org/10.7499/j.issn.1008-8830.2309038

Center for Diagnosis and Treatment of Kawasaki Disease/Children's Hospital of Shaanxi Provincial People's Hospital, National Children's Medical Center/Beijing Children's Hospital, Capital Medical University, Children's Hospital, Shanghai Jiao Tong University School of Medicine, National Regional Medical Center/Shengjing Hospital of China Medical University, National Clinical Key Specialty/Department of Intensive Care Medicine, Shanghai Children's Hospital, General Pediatric Group of Pediatrician Branch of Chinese Medical Doctor Association, Expert Committee of Advanced Training for Pediatrician, China Maternal and Children's Health Association, National Health Commission Key Laboratory for Tropical Disease Prevention and Control, Yan'an University Affiliated Hospital, Editorial Department of Chinese Journal of Contemporary Pediatrics. Evidence-based guidelines for the diagnosis and treatment of Kawasaki disease in children in China (2023)[J]. Chinese Journal of Contemporary Pediatrics. 2023, 25(12): 1198-1210 https://doi.org/10.7499/j.issn.1008-8830.2309038

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