儿科输血的现状与未来

王天有, 李拓章

中国当代儿科杂志 ›› 2024, Vol. 26 ›› Issue (12) : 1245-1248.

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中国当代儿科杂志 ›› 2024, Vol. 26 ›› Issue (12) : 1245-1248. DOI: 10.7499/j.issn.1008-8830.2405048
专家述评

儿科输血的现状与未来

  • 王天有, 李拓章
作者信息 +

The current situation and the future of pediatric blood transfusion

  • WANG Tian-You, LI Tuo-Zhang
Author information +
文章历史 +

摘要

随着临床医学的发展,儿科输血已从传统的经验性输血转变为基于临床研究数据的循证输血。为了更好地指导儿科输血实践,改善患儿的临床结局,国家卫生健康委员会制定并发布了《儿科输血指南》。该文概述儿科患者输血的特殊性、血液成分输注在儿童患者治疗中的应用、《儿科输血指南》解读的意义,并展望儿科输血医学发展的前景。

Abstract

With advancements in clinical medicine, pediatric blood transfusion has evolved from traditional empirical practices to evidence-based approaches grounded in clinical research data. To better guide pediatric blood transfusion practices and improve clinical outcomes for pediatric patients, the National Health Commission has developed and issued "Guideline for pediatric transfusion". This article summarizes the unique aspects of pediatric blood transfusion, the application of blood component therapy in treating pediatric patients, the significance of interpreting the "Guideline for pediatric transfusion", and anticipates future developments in pediatric blood transfusion medicine.

关键词

儿科输血 / 血液成分 / 循证医学

Key words

Pediatric blood transfusion / Blood component / Evidence-based medicine

引用本文

导出引用
王天有, 李拓章. 儿科输血的现状与未来[J]. 中国当代儿科杂志. 2024, 26(12): 1245-1248 https://doi.org/10.7499/j.issn.1008-8830.2405048
WANG Tian-You, LI Tuo-Zhang. The current situation and the future of pediatric blood transfusion[J]. Chinese Journal of Contemporary Pediatrics. 2024, 26(12): 1245-1248 https://doi.org/10.7499/j.issn.1008-8830.2405048

参考文献

1 Josephson CD, Luban NL. Pediatric and neonatal transfusion medicine: a roadmap for research[J]. Transfus Med Rev, 2016, 30(4): 157-158. PMID: 27555063. PMCID: PMC5874793. DOI: 10.1016/j.tmrv.2016.08.003.
2 Cohn CS, Delaney M, Johnson ST, et al. Technical Manual[M]. 20th ed. Bethesda: American Association of Blood Banks, 2020: 771.
3 Wang Y, Sun W, Wang X, et al. Comparison of transfusion reactions in children and adults: a systematic review and meta-analysis[J]. Pediatr Blood Cancer, 2022, 69(9): e29842. PMID: 35758531. DOI: 10.1002/pbc.29842.
4 Sostin N, Hendrickson JE. Pediatric hemovigilance and adverse transfusion reactions[J]. Clin Lab Med, 2021, 41(1): 51-67. PMID: 33494885. DOI: 10.1016/j.cll.2020.10.004.
5 New HV, Grant-Casey J, Lowe D, et al. Red blood cell transfusion practice in children: current status and areas for improvement? A study of the use of red blood cell transfusions in children and infants[J]. Transfusion, 2014, 54(1): 119-127. PMID: 23808415. DOI: 10.1111/trf.12313.
6 Patterson JA, Bowen JR, Francis S, et al. Comparison of neonatal red cell transfusion reporting in neonatal intensive care units with blood product issue data: a validation study[J]. BMC Pediatr, 2018, 18(1): 86. PMID: 29475432. PMCID: PMC5824461. DOI: 10.1186/s12887-018-1005-2.
7 Keir AK, Yang J, Harrison A, et al. Temporal changes in blood product usage in preterm neonates born at less than 30 weeks' gestation in Canada[J]. Transfusion, 2015, 55(6): 1340-1346. PMID: 25652740. DOI: 10.1111/trf.12998.
8 Franz AR, Engel C, Bassler D, et al. Effects of liberal vs restrictive transfusion thresholds on survival and neurocognitive outcomes in extremely low-birth-weight infants: the ETTNO randomized clinical trial[J]. JAMA, 2020, 324(6): 560-570. PMID: 32780138. PMCID: PMC7420159. DOI: 10.1001/jama.2020.10690.
9 Case RB, Berglund E, Sarnoff SJ. Ventricular function. VII. Changes in coronary resistance and ventricular function resulting from acutely induced anemia and the effect thereon of coronary stenosis[J]. Am J Med, 1955, 18(3): 397-405. PMID: 14349964. DOI: 10.1016/0002-9343(55)90219-9.
10 Yawn BP, Buchanan GR, Afenyi-Annan AN, et al. Management of sickle cell disease: summary of the 2014 evidence-based report by expert panel members[J]. JAMA, 2014, 312(10): 1033-1048. PMID: 25203083. DOI: 10.1001/jama.2014.10517.
11 Josephson CD, Granger S, Assmann SF, et al. Bleeding risks are higher in children versus adults given prophylactic platelet transfusions for treatment-induced hypoproliferative thrombocytopenia[J]. Blood, 2012, 120(4): 748-760. PMID: 22538854. PMCID: PMC3462047. DOI: 10.1182/blood-2011-11-389569.
12 Curley A, Stanworth SJ, Willoughby K, et al. Randomized trial of platelet-transfusion thresholds in neonates[J]. N Engl J Med, 2019, 380(3): 242-251. PMID: 30387697. DOI: 10.1056/NEJMoa1807320.
13 Sola-Visner MC. Platelet transfusions in neonates-less is more[J]. N Engl J Med, 2019, 380(3): 287-288. PMID: 30650325. DOI: 10.1056/NEJMe1813419.
14 Mo YD, Delaney M. Transfusion in pediatric patients: review of evidence-based guidelines[J]. Clin Lab Med, 2021, 41(1): 1-14. PMID: 33494878. DOI: 10.1016/j.cll.2020.10.001.
15 Stanworth SJ, Grant-Casey J, Lowe D, et al. The use of fresh-frozen plasma in England: high levels of inappropriate use in adults and children[J]. Transfusion, 2011, 51(1): 62-70. PMID: 20804532. DOI: 10.1111/j.1537-2995.2010.02798.x.
16 Tinmouth A, Thompson T, Arnold DM, et al. Utilization of frozen plasma in Ontario: a provincewide audit reveals a high rate of inappropriate transfusions[J]. Transfusion, 2013, 53(10): 2222-2229. PMID: 23672421. DOI: 10.1111/trf.12231.
17 Leeper CM, Neal MD, Billiar TR, et al. Overresuscitation with plasma is associated with sustained fibrinolysis shutdown and death in pediatric traumatic brain injury[J]. J Trauma Acute Care Surg, 2018, 85(1): 12-17. PMID: 29443859. DOI: 10.1097/TA.0000000000001836.
18 马婷, 宋奥微, 孙杨, 等. 新生儿输血热点调查[J]. 临床血液学杂志, 2019, 32(8): 632-635. DOI: 10.13201/j.issn.1004-2806-b.2019.08.019.
19 Kirpalani H, Bell EF, Hintz SR, et al. Higher or lower hemoglobin transfusion thresholds for preterm infants[J]. N Engl J Med, 2020, 383(27): 2639-2651. PMID: 33382931. PMCID: PMC8487591. DOI: 10.1056/NEJMoa2020248.
20 Curley A, Stanworth SJ, Willoughby K, et al. Randomized trial of platelet-transfusion thresholds in neonates[J]. N Engl J Med, 2019, 380(3): 242-251. PMID: 30387697. DOI: 10.1056/NEJMoa1807320.
21 Lacroix J, Hébert PC, Hutchison JS, et al. Transfusion strategies for patients in pediatric intensive care units[J]. N Engl J Med, 2007, 356(16): 1609-1619. PMID: 17442904. DOI: 10.1056/NEJMoa066240.
22 中华人民共和国国家卫生健康委员会法规司. 关于发布《输血相容性检测标准》等3项推荐性卫生行业标准的通告: 国卫通〔2022〕1号[EB/OL]. (2022-02-23)[2024-05-10]. http://www.nhc.gov.cn/fzs/s7852d/202202/1484f47dcf824ee8bae3ad7b6809e603.shtml.
23 National Institutes of Health. NIH policy and guidelines on the inclusion of children as participants in research involving human subjects[EB/OL]. (1998-03-06)[2024-05-01]. http://grants.nih.gov/grants/guide/notice-files/not98-024.html.
24 Spitalnik SL, Triulzi D, Devine DV, et al. 2015 proceedings of the National Heart, Lung, and Blood Institute's State of the Science in Transfusion Medicine symposium[J]. Transfusion, 2015, 55(9): 2282-2290. PMID: 26260861. PMCID: PMC4573332. DOI: 10.1111/trf.13250.

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