早产儿贫血诊断与治疗的临床实践指南（2025年）

海峡两岸医药卫生交流协会新生儿临床实践指南专家委员会; 海峡两岸医药卫生交流协会 新生儿学专业委员会新生儿循证医学学组; 《中国当代儿科杂志》编辑部

doi:10.7499/j.issn.1008-8830.2407094

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中国当代儿科杂志 ›› 2025, Vol. 27 ›› Issue (1) : 1-17. DOI: 10.7499/j.issn.1008-8830.2407094

标准·方案·指南

早产儿贫血诊断与治疗的临床实践指南（2025年）

海峡两岸医药卫生交流协会新生儿临床实践指南专家委员会；海峡两岸医药卫生交流协会新生儿学专业委员会新生儿循证医学学组；《中国当代儿科杂志》编辑部

作者信息 +

Clinical practice guidelines for the diagnosis and treatment of anemia of prematurity (2025)

Neonatal Clinical Practice Guidelines Expert Committee of the Cross-Strait Medical and Health Exchange Association; Neonatal Evidence-Based Medicine Group of the Commission of Neonatal Medicine of the Cross-Strait Medical and Health Exchange Association; Editorial Office of the Chinese Journal of Contemporary Pediatrics

Author information +

文章历史 +

摘要

早产儿贫血（anemia of prematurity, AOP）是一种多因素疾病，与先天储铁不足、促红细胞生成素水平低、红细胞寿命短以及医源性失血等有关。AOP是早产儿的常见并发症，影响生长发育和远期神经认知发育。为规范AOP的诊断与治疗，基于世界卫生组织指南制订手册和中国临床诊疗指南制订/修订指导原则，海峡两岸医药卫生交流协会新生儿临床实践指南专家委员会和新生儿学专业委员会新生儿循证医学学组及《中国当代儿科杂志》编辑部共同制定了《早产儿贫血诊断与治疗的临床实践指南（2025年）》。该指南针对AOP的危险因素、早期识别、病因诊断、诊断标准、早期预防、输血治疗、如何改善预后及出院后随访8个临床问题，基于目前证据和专家共识形成了29条推荐意见，以期为医护人员在AOP诊断与治疗方面提供指导与决策依据。

Abstract

Anemia of prematurity (AOP) is a multifactorial condition associated with congenital iron deficiency, low erythropoietin levels, a short lifespan of red blood cells, and iatrogenic blood loss. AOP is a common complication in premature infants that can adversely affect growth, development, and long-term neurocognitive outcomes. To standardize the diagnosis and treatment of AOP, the Neonatal Clinical Practice Guidelines Expert Committee and the Neonatal Evidence-Based Medicine Group of the Commission of Neonatal Medicine of the Cross-Strait Medical and Health Exchange Association, along with the Editorial Office of the Chinese Journal of Contemporary Pediatrics, have developed the "Clinical practice guidelines for the diagnosis and treatment of anemia of prematurity (2025)", based on the World Health Organization's handbook for guideline development and the formulation/revision principles of Chinese clinical practice guidelines. This guideline addresses eight clinical issues related to AOP, including risk factors, early identification, etiological diagnosis, diagnostic criteria, early prevention, transfusion therapy, strategies to improve prognosis, and post-discharge follow-up. It presents 29 recommendations formed from current evidence and expert consensus, aiming to provide guidance and decision-making support for healthcare professionals in the diagnosis and treatment of AOP.

导出引用

海峡两岸医药卫生交流协会新生儿临床实践指南专家委员会；海峡两岸医药卫生交流协会新生儿学专业委员会新生儿循证医学学组；《中国当代儿科杂志》编辑部. 早产儿贫血诊断与治疗的临床实践指南（2025年）[J]. 中国当代儿科杂志. 2025, 27(1): 1-17 https://doi.org/10.7499/j.issn.1008-8830.2407094

Neonatal Clinical Practice Guidelines Expert Committee of the Cross-Strait Medical and Health Exchange Association; Neonatal Evidence-Based Medicine Group of the Commission of Neonatal Medicine of the Cross-Strait Medical and Health Exchange Association; Editorial Office of the C. Clinical practice guidelines for the diagnosis and treatment of anemia of prematurity (2025)[J]. Chinese Journal of Contemporary Pediatrics. 2025, 27(1): 1-17 https://doi.org/10.7499/j.issn.1008-8830.2407094

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