目的 分析1990—2021年我国儿童和青少年传染病的流行病学特点和变化趋势。 方法 基于全球疾病负担数据库,选取1990—2021年我国20岁以下人群传染病的流行病学指标,对该人群传染病疾病负担进行分析,并与全球、西欧、北美等地区进行比较。 结果 1990年—2021年,我国儿童和青少年整体传染病疾病负担呈下降趋势。2021年我国传染病患病率低于全球患病率,但高于西欧、北美同期水平。传染病死亡率明显下降,与西欧、北美的差距逐年缩小。男性整体传染病发病率、死亡率和伤残调整寿命年率均高于女性,呼吸道感染、肠道感染在5岁以下儿童中更常见,而青少年性传播疾病发病率更高。 结论 1990—2021年,我国20岁以下人群传染病疾病负担明显下降,但较于发达地区仍有一定差距,加强对呼吸道感染和艾滋病等疾病的防控,加强5岁以下儿童的健康干预,有助于提高我国儿童和青少年整体健康水平。 中国当代儿科杂志,2025,27(1):39-46]
Abstract
Objective To investigate the epidemiological characteristics and changing trends of communicable diseases among children and adolescents in China from 1990 to 2021. Methods Based on the Global Burden of Disease Database, epidemiological indicators for communicable diseases among the population aged under 20 years in China from 1990 to 2021 were selected to analyze the burden of communicable diseases in this population, and a comparative analysis was performed with global data as well as data from Western Europe and North America. Results In 1990-2021, the overall burden of communicable diseases tended to decrease among children and adolescents in China. In 2021, the prevalence rate of communicable diseases in China was lower than the global prevalence rate and was higher than that in Western Europe and North America. There was a significant reduction in the mortality rate of communicable diseases, and the gap with Western Europe and North America gradually narrowed year by year. The overall incidence rate, mortality rate, and disability-adjusted life year rate of communicable diseases in males were higher than those in females, and respiratory infections and intestinal infections were more common in children aged <5 years, while the incidence rate of sexually transmitted diseases was higher in adolescents. Conclusions From 1990 to 2021, the disease burden of communicable diseases among the population under 20 years old in China has significantly decreased. However, there is still a certain gap compared to developed regions. Strengthening the prevention and control of diseases such as respiratory infections and acquired immunodeficiency syndrome, as well as enhancing health interventions for children under 5 years old, will help improve the overall health level of children and adolescents in China.
关键词
全球疾病负担数据库 /
中国 /
传染病 /
儿童 /
青少年
Key words
Global Burden of Disease Database /
China /
Communicable disease /
Child /
Adolescent
{{custom_sec.title}}
{{custom_sec.title}}
{{custom_sec.content}}
参考文献
1 杨维中, 贾萌萌. 中国消除传染病的历史进程与展望[J]. 中华流行病学杂志, 2021, 42(11): 1907-1911. PMID: 34818832. DOI: 10.3760/cma.j.cn112338-20211016-00801.
2 陈永平. 全球新发传染病的挑战与防控[J]. 中华传染病杂志, 2018, 36(7): 393-396. DOI: 10.3760/cma.j.issn.1000-6680.2018.07.002.
3 Zhang C, Fu X, Liu Y, et al. Burden of infectious diseases and bacterial antimicrobial resistance in China: a systematic analysis for the Global Burden of Disease Study 2019[J]. Lancet Reg Health West Pac, 2023, 43: 100972. PMID: 38076321. PMCID: PMC10700598. DOI: 10.1016/j.lanwpc.2023.100972.
4 冯文雅, 姚云花, 赵成松, 等. 2007年至2021年北京市单中心儿童传染病的流行特征分析[J]. 中华传染病杂志, 2023, 41(7): 447-453. DOI: 10.3760/cma.j.cn311365-20221215-00502.
5 GBD 2019 Child and Adolescent Communicable Disease Collaborators. The unfinished agenda of communicable diseases among children and adolescents before the COVID-19 pandemic, 1990-2019: a systematic analysis of the Global Burden of Disease Study 2019[J]. Lancet, 2023, 402(10398): 313-335. PMID: 37393924. PMCID: PMC10375221. DOI: 10.1016/S0140-6736(23)00860-7.
6 GBD 2019 Under-5 Mortality Collaborators. Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health: all-cause and cause-specific mortality findings from the Global Burden of Disease Study 2019[J]. Lancet, 2021, 398(10303): 870-905. PMID: 34416195. PMCID: PMC8429803. DOI: 10.1016/S0140-6736(21)01207-1.
7 GBD 2021 Diseases and Injuries Collaborators. Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021[J]. Lancet, 2024, 403(10440): 2133-2161. PMID: 38642570. PMCID: PMC11122111. DOI: 10.1016/S0140-6736(24)00757-8.
8 周宇辉. 我国传染病流行现状与防控体系建设研究[J]. 中国卫生政策研究, 2023, 16(4): 74-78. DOI: 10.3969/j.issn.1674-2982.2023.04.011.
9 贾彦辉, 李湘黔, 汤薪玉. 中国共产党百年治疫: 历程、成就与经验[J]. 湖北行政学院学报, 2021(1): 74-81. DOI: 10.3969/j.issn.1671-7155.2021.01.012.
10 龚如涵, 刘庆中, 陈沭, 等. 上海市松江区0~12岁上呼吸道感染患儿7种常见病毒流行病学特征[J]. 检验医学, 2019, 34(12): 1097-1100. DOI: 10.3969/j.issn.1673-8640.2019.12.008.
11 张昕婷, 张俊英, 曹爱华. 济南市1 300例儿童呼吸道疾病流行病学分析[J]. 中华流行病学杂志, 2014, 35(11): 1275-1277. DOI: 10.3760/cma.j.issn.0254-6450.2014.11.022.
12 Perin J, Mulick A, Yeung D, et al. Global, regional, and national causes of under-5 mortality in 2000-19: an updated systematic analysis with implications for the Sustainable Development Goals[J]. Lancet Child Adolesc Health, 2022, 6(2): 106-115. PMID: 34800370. PMCID: PMC8786667. DOI: 10.1016/S2352-4642(21)00311-4.
13 Rossi GA, Medici MC, Arcangeletti MC, et al. Risk factors for severe RSV-induced lower respiratory tract infection over four consecutive epidemics[J]. Eur J Pediatr, 2007, 166(12): 1267-1272. PMID: 17308898. PMCID: PMC2042510. DOI: 10.1007/s00431-007-0418-y.
14 张文, 余雅, 范君, 等. 2016—2020年重庆市学生肺结核流行病学特征分析[J]. 中国防痨杂志, 2022, 44(8): 784-791. DOI: 10.19982/j.issn.1000-6621.20220196.
15 Zheng Y, Yu Q, Lin Y, et al. Global burden and trends of sexually transmitted infections from 1990 to 2019: an observational trend study[J]. Lancet Infect Dis, 2022, 22(4): 541-551. PMID: 34942091. DOI: 10.1016/S1473-3099(21)00448-5.
16 杜莉, 王天景, 朱丽萍. 上海市性病门诊青少年患者知信行的现状调查[J]. 上海预防医学, 2021, 33(6): 514-520. DOI: 10.19428/j.cnki.sjpm.2021.20010.
17 杨雨晴, 张琬悦, 张小斌, 等. 青少年生殖道沙眼衣原体和淋球菌感染现况与防控措施[J]. 皮肤病与性病, 2023, 45(1): 49-52. DOI: 10.3969/j.issn.1002-1310.2023.01.012.
18 姜路明, 朱匡纪, 楼秒芬, 等. 金华市婺城区儿童青少年梅毒流行特征分析[J]. 中国初级卫生保健, 2018, 32(12): 42-44. DOI: 10.3969/j.issn.1001-568X.2018.12.0015.
19 林小丹, 毛秀华, 姚卫光. 2008—2018年中国肠道传染病流行特征及空间聚集性分析[J]. 中国全科医学, 2023, 26(4): 417-425. DOI: 10.12114/j.issn.1007-9572.2022.0612
20 简慧, 陈泽伟, 岳晓丽, 等. 2018—2023年中国生殖道沙眼衣原体感染流行趋势及时空分布特征[J]. 中华皮肤科杂志, 2024, 57(5): 450-454. DOI: 10.35541/cjd.20240038.