目的 从神经心理角度来探讨Tourette综合征(TS)的发病机理。方法 采用韦氏儿童智力量表(WISC-CR)对21例TS患儿进行了神经心理测验，并分别于治疗前后与20例正常儿童进行比较。结果 TS组总智商、言语智商、操作智商与正常对照无显著差异，但分测验：迷津、译码、背数均低于对照组(P<0.05)，TS患儿治疗前后各项指标无明显变化(P>0.05)。结论 结果表明TS患儿神经心理存在不同程度的缺陷，提示除药物治疗外，还应给予TS患儿适当的心理干预。

Objective The aim of the study was to investigate the pathogenesis of Tourette syndrome(TS) by means of neuropsychology.Methods The neuropsychological tests were performed by Wechsler Intelligence Scale for Chinese-Children Revised(WISC-CR) in 21 children with TS.The results before and after therapy were compared with that of 20 normal children, respectively.Results The scale scores of labyrinth , coding , digit span and scores of lie scale in the TS group were significantly lower than those in normal children ( P <0.05), but there was no obvious diffence between the group TS and the normal group in the total intelligence , language intelligence, and operating intelligence.There was no obvious change in the status of the TS group after treatment. Conclusions Children with TS have neuropsychological deficit in various degrees and in addition to administration of medicine, psychological treatment is necessary.